Heart Disease Trial, Recruiting NCT05635227 Sponsor: Rigshospitalet, Denmark Condition: Heart Disease
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Heart Disease Trial, Recruiting

NCT05635227
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who are 18 years of age or older
  • People who are scheduled for coronary artery bypass grafting (heart bypass surgery) and/or aortic valve replacement, regardless of whether other valve surgery is also being performed at the same time

Who may not be able to join:

  • People whose surgery is unplanned or scheduled outside of regular hours (emergency or urgent surgery)
  • People who are pregnant or currently breastfeeding (pregnancy testing will be done before enrolment to rule this out in all women who could potentially become pregnant)
  • People who have a known heart valve infection (endocarditis) at the time of screening
  • People who have previously taken part in this same trial
  • People who currently have an active infection of any kind, including bacterial, viral, or fungal infections
  • People who have known liver cirrhosis (serious scarring of the liver)
  • People with a known severely low platelet count (the blood cells that help with clotting) below a certain level
  • People with a known severely low white blood cell count below a certain level
  • People who are currently on a waiting list to receive a heart transplant
  • People who have previously received a major organ transplant
  • People who have certain specific heart or thyroid conditions, including a thickened heart muscle that blocks blood flow, active inflammation of the heart, stiffening of the heart's surrounding sac, or an untreated overactive or underactive thyroid
  • People who have received chemotherapy or radiation therapy for cancer within the last 6 months
  • People who currently have evidence of active cancer, except for certain low-risk skin cancers, a specific type of cervical cell change, or stable prostate cancer
  • People with a known eye condition called narrow-angle glaucoma
  • People with a known condition called phenylketonuria (a rare inherited condition affecting how the body processes a certain amino acid)
  • People with Type 1 diabetes
  • People with a known heart rhythm condition called long QT syndrome
  • People with a known allergy to any of the medications being used in the study
  • People whose participation the trial investigators believe could put them at risk, affect the reliability of the results, or significantly interfere with their ability to take part
  • People with certain blood vessel disease outside of the heart (identified through a standard pre-surgical assessment) will not be eligible for one specific part of the trial related to blood flow management during surgery (confirm with trial site)

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 26 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Christian Hassager, MD, DMSc, Sponsor GmbH

Phone: +45 35 45 17 10

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Registry
ClinicalTrials.gov
Start date
10 November 2022
Est. completion
1 December 2027

Where this trial is recruiting

🇩🇰 Denmark

Primary endpoints

Days alive and outside hospital

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 26 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov