Cardiomyopathy Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- Adults aged 18 or older
- People whose heart's pumping strength (measured as the left ventricle ejection fraction, or LVEF) has been recorded at 50% or below within the past 6 months
- People who have had an electrical heart tracing (ECG) showing a delayed or widened electrical signal in the heart (QRS duration of 130 milliseconds or more), OR whose heart is expected to rely heavily on pacemaker pacing from the right side of the heart (more than 40% of the time), OR who already have a device in place that paces the right side of the heart more than 40% of the time
- People who are already receiving the recommended standard medications for heart failure, OR whose doctor plans to work toward starting and adjusting those medications as much as their health allows before any procedure takes place
Who may not be able to join:
- Women who are pregnant, currently breastfeeding, or planning to become pregnant during the trial
- People who have blocked heart arteries and are likely to need a heart bypass operation or an artery-opening procedure (such as a stent) within the next 3 months
- People who have had a heart attack (confirmed by enzyme blood tests) within the past 3 months
- People who have had heart bypass surgery or an artery-opening procedure (such as balloon or stent treatment) within the past 3 months
- People whose weakened heart muscle is caused by a temporary or reversible condition (for example, a recent viral infection of the heart)
- People diagnosed with Chagas disease, cardiac sarcoidosis, or cardiac amyloidosis
- People expected to need a mechanical heart pump (left ventricular assist device) or a heart transplant within 6 months
- People with serious heart valve disease as their primary condition (for example, severe aortic stenosis)
- People whose life expectancy is less than 12 months
- People who have permanent brain damage caused by a pre-existing brain condition
- People who are allergic to contrast dye used in imaging and are either unable or unwilling to take pre-treatment medications (steroids and/or an antihistamine) to manage that allergy
- People currently taking part in another interventional heart-related clinical trial
- People who would not be able to attend the scheduled follow-up visits required by the study
- People who have previously had an unsuccessful attempt at implanting a biventricular pacemaker, His bundle pacing device, or left bundle branch pacing device
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Mihail G Chelu, MD, PhD, Baylor College of Medicine
Phone: 7137987291
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
A combined clinical endpoint of all-cause mortality and hospitalization for heart failure
Can't join this trial?
Data last synced from ClinicalTrials.gov: 27 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.