Alzheimer's Disease Trial, Recruiting
voxsanity.com.au · Eligibility summary from public government registries · 18 August 2026 · not medical advice
Who may and may not be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who may be able to join
- People between the ages of 65 and 100.
- People who have been diagnosed with mild Alzheimer's disease, with a specific memory and thinking test score (called the MMSE) between 19 and 26.
- People who are willing to sign a consent form agreeing to take part. If a person is not able to sign for themselves, a legally authorised representative may be able to sign on their behalf.
- People who are able to complete the first month of at-home treatment sessions at their main place of residence. If more than one week away from home is planned during the trial, the research team would need to assess whether participation is still possible.
Who may not be able to join
Each point below is a reason the trial team may not be able to accept someone. It is not a list of requirements to meet.
- People who do not have health insurance or healthcare coverage.
- People who are currently taking a medication that reduces amyloid (a protein linked to Alzheimer's disease) in the brain.
- People who have more than 4 small bleeds or 1 large bleed in the brain (identified on a brain scan).
- People who have been taking psychiatric medications (such as antidepressants or antipsychotics) at their current dose for less than three months. A stable dose taken for three months or more is generally acceptable.
- People who are currently being treated for an active cancer diagnosis.
- People who are taking a type of medication called NMDA receptor antagonists, such as Memantine.
- People taking medications that are known to lower the threshold for seizures, such as bupropion (Wellbutrin), ciprofloxacin, or levofloxacin.
- People with a personal history of seizures or epilepsy.
- People with a significant risk of suicide or who have had a suicide attempt in the past 12 months.
- People with behavioural challenges such as aggression, agitation, or impulsivity that may make it difficult to follow the trial's requirements.
- People with depression that is untreated or not currently stable.
- People currently taking any anti-epileptic (anti-seizure) medication.
- People who have had a stroke in the past 24 months.
- People who have had eye surgery in the last 3 months or who have eye surgery planned within the next 6 months during the study period.
- People who have been diagnosed with migraine headaches.
- People who have an active implanted medical device, such as a heart pacemaker, implantable defibrillator, deep brain stimulator, or sacral nerve stimulator.
- People with severe hearing or vision loss.
- People with a life expectancy of less than 2 years.
- People who are pregnant.
- People with a history of any neurological condition other than dementia, such as epilepsy, stroke, a progressive neurological disease (for example, multiple sclerosis), brain lesions, previous brain surgery, or a head injury that caused lasting neurological effects.
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
If you need support right now
This page includes language about suicide and self-harm, because that is how the trial's eligibility criteria are written. If reading it has been hard, you do not have to keep going. The services below are free, confidential, and answered by people trained for exactly this.
If you or someone else is in immediate danger, call 000.
- Lifeline — 24/7 crisis support: 13 11 14
- Suicide Call Back Service — 24/7 counselling: 1300 659 467
- 13YARN — 24/7, for Aboriginal and Torres Strait Islander people: 13 92 76
- Beyond Blue — 24/7 mental health support: 1300 22 4636
- Emergency: 000
Outside Australia? The numbers above are Australian and will not work from overseas. Find a Helpline is a free directory of crisis lines in over 130 countries, run by ThroughLine with the International Association for Suicide Prevention. If you are in immediate danger, call your local emergency number.
Voxsanity is not a crisis service, and nothing on this page is medical advice. More Australian services are listed on our support lines page.
If this is close to home
This page includes language about advanced illness, prognosis, or palliative care, because that is how the trial's eligibility criteria are written. Seeing it set out plainly can land hard, whether it is about you or about someone you are caring for. You do not have to be at a crisis point to talk to someone.
- Griefline — grief and loss counselling, 9am to 6pm weekdays and midday to 6pm weekends (AEST/AEDT): 1300 845 745
- Carer Gateway — practical and emotional support if you are caring for someone, 8am to 5pm weekdays: 1800 422 737
- Canteen — for 12 to 25 year olds affected by cancer, their own or a family member's: 1800 945 215
- Palliative Care Australia — directory of palliative care services near you: palliativecare.org.au
- Lifeline — 24/7, for any kind of distress, at any hour the services above are closed: 13 11 14
Palliative care is not the same as giving up on treatment, and it is not only for the last weeks of life. It is symptom and comfort care that can run alongside active treatment, including a clinical trial.
Outside Australia? The numbers above are Australian and will not work from overseas. Find a Helpline is a free directory of support and crisis lines in over 130 countries, run by ThroughLine with the International Association for Suicide Prevention.
Voxsanity is not a counselling or medical service, and nothing on this page is medical advice. More Australian services are listed on our support lines page.
Contact this trial
Principal Investigator: Li Huei Tsai, PhD, Massachusetts Institute of Technology
Phone: 617-258-7723
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Feasibility of gamma frequency stimulation as assessed by a change of gamma frequency waves during EEG; Baseline incidence of stimulation-related adverse symptoms and side effects as assessed by post-stimulation questionnaires; Mid-point incidence of stimulation-related adverse symptoms and side effects as assessed by post-stimulation questionnaires; Endpoint incidence of stimulation-related adverse symptoms and side effects as assessed by post-stimulation questionnaires; Change in stimulation-related adverse symptoms and side effects as assessed by post-stimulation questionnaires; Changes in...
Can't join this trial?
Data last synced from ClinicalTrials.gov: 31 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.