Phase 1 Sleep Disorders Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- People who have been diagnosed with Mucopolysaccharidosis type I Hurler-Scheie or Scheie syndrome.
- People who are 10 years of age or older at the time of registering for the study.
- People whose kidneys are functioning well enough, as shown by a kidney filtering rate above a certain level (confirm with trial site for exact measurement method).
- People whose heart is pumping effectively, as confirmed by a heart ultrasound showing the heart is working at or above the required level.
- People who are able and willing to travel to the study site for required check-up appointments.
- People who are able to stay within a 45-minute drive of the study site for at least 5 days after receiving the cell treatment.
Who may not be able to join:
- People with a known inherited cancer syndrome that runs in their family, or those with a suspected case that is found to carry certain genetic mutations after testing.
- People with a history of a cancer affecting B cells, a condition called EBV lymphoproliferative disease, or autoimmune disorders.
- People who currently show signs of a condition called graft-versus-host disease (where previously transplanted cells attack the body).
- People who have previously received a blood stem cell transplant.
- People who currently need ongoing medication to suppress their immune system.
- People who require continuous extra oxygen to breathe.
- People with any other health condition that the medical team believes could interfere with assessing whether the treatment is safe or working.
- People who, in the opinion of the study doctor, are unlikely to attend all required appointments or follow the study's requirements.
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Number of participants with treatment-related adverse events and serious adverse events
Can't join this trial?
Data last synced from ClinicalTrials.gov: 12 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.