Sleep Disorders Trial, Recruiting NCT05684094 Sponsor: University of Oregon Condition: Sleep Disorders
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Sleep Disorders Trial, Recruiting

NCT05684094
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who are between 18 and 24 years old
  • People who drink alcohol at high-risk levels in the past month — for women, this means 4 or more drinks in a day or 8 or more drinks per week; for men, 5 or more drinks in a day or 15 or more drinks per week
  • People whose sleep on weekdays is either short and late (7.5 hours or less of sleep, going to bed at midnight or later) or long and early (more than 7.5 hours of sleep, going to bed before midnight)
  • People who have experienced at least a moderate level of stressful or difficult life events (scoring 2 or more on a standard 20-item life stress checklist)
  • People who are not currently attending high school
  • People who are fluent in English

Who may not be able to join:

  • People with a severe alcohol or substance use disorder, as assessed using standard diagnostic guidelines
  • People who show alcohol in their system (a blood alcohol level of 0.02 or higher on a breathalyzer test) on the days of certain lab visits — though a reschedule may be offered
  • People who currently have a doctor-diagnosed sleep disorder called narcolepsy or idiopathic hypersomnia
  • People who have ever been diagnosed with bipolar disorder or a schizophrenia-related condition
  • People with certain serious medical conditions, such as a significant neurological disorder, serious heart problems, or a history of head injury that caused unconsciousness for more than 5 minutes
  • People with certain conditions or implants that make MRI scans unsafe (for example, having ferrous metal in the body)
  • People who report having an eye disease, epilepsy, or who take certain medications that are not safe when exposed to bright light — such as some psychiatric, antimalarial, heart rhythm, or skin treatment medications (confirm with trial site)
  • People who use melatonin and are not willing to stop taking it for the full duration of the study

Scheduling may be adjusted (appointments delayed) for people in these situations:

  • Those assessed as being at urgent or serious risk of suicide at the time of a visit
  • Those who have travelled across two or more time zones within the month before an overnight study visit
  • Those who have started or stopped a prescribed medication within 2 months of the overnight study visits
  • Those whose medication dose has recently changed within a timeframe based on how long that medication takes to stabilise in the body (confirm specific timeframe with trial site)
  • Those who expect to change their medications or doses during the study period
  • Those who have current symptoms of an airborne illness such as COVID-19 before a lab visit

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 19 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Melynda D Casement, PhD, University of Oregon

Phone: 541-346-4107

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
University of Oregon
Registry
ClinicalTrials.gov
Start date
7 September 2023
Est. completion
28 February 2027

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Alcohol use; Reward-related brain function; Stress-related brain function

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 19 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov