Phase 2 Liver Cancer Trial, Recruiting NCT05775146 Sponsor: AHS Cancer Control Alberta Condition: Liver Cancer
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Phase 2 Liver Cancer Trial, Recruiting

NCT05775146
Recruiting Phase 2

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You must be 18 years of age or older
  • You must be well enough to carry out daily activities, either fully or with some limitations (your doctor can confirm if your fitness level qualifies)
  • You must be able to sign a written consent form agreeing to take part
  • You must have between 1 and 5 liver spots (lesions), with any single one being no larger than 5cm, all located in one section of the liver, and a specialist medical team must agree they could be treated with a precise form of radiation therapy (SBRT) with the aim of curing you
  • Your liver spots must have been found within 3 months of your original cancer diagnosis, and a specialist team must agree they may be suitable for SBRT with curative intent
  • There must be a plan to surgically remove your original (primary) cancer tumour with the aim of curing you
  • If you also have spots on your lungs that could potentially be removed or treated, you may still be eligible
  • If you have colon cancer and have already had your primary colon tumour removed, you may still be eligible
  • You must be willing and able to follow the study requirements, including filling in quality-of-life questionnaires
  • Women who could become pregnant must have a negative pregnancy test at the start of the study (confirm with trial site for full details)
  • Male patients must agree not to donate sperm during the study

Who may not be able to join:

  • You have cancer that has spread to areas of the body outside the liver, other than lung spots that could potentially be removed or treated
  • You are not considered suitable for liver surgery
  • You are not considered suitable for the specialist radiation treatment (SBRT) used in this trial
  • You have had another cancer diagnosed within the last 5 years (except a type of common skin cancer called basal cell carcinoma)
  • You have previously had surgery or a tissue-destruction procedure (ablation) on your liver lesions
  • There is a plan to remove both your primary tumour and your liver spots at the same time in one operation
  • You are currently pregnant
  • You are currently breastfeeding
  • You have a severe form of liver scarring (cirrhosis) classified as Child-Pugh C (confirm with trial site)

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 5 July 2026
Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Aswin Abraham, Cross Cancer Institute, Alberta Health Services

Phone: 780-432-8516

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 2
Sponsor
AHS Cancer Control Alberta
Registry
ClinicalTrials.gov
Start date
18 June 2024
Est. completion
30 June 2028

Where this trial is recruiting

🇨🇦 Canada

Primary endpoints

Progression free survival (PFS)

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 5 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov