Sleep Disorders Trial, Recruiting NCT05775627 Sponsor: Oregon Health and Science University Condition: Sleep Disorders
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Sleep Disorders Trial, Recruiting

NCT05775627
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • Adults between 18 and 40 years of age
  • People who are not currently using any drugs (including caffeine, nicotine, alcohol, and herbal medications)
  • People who have been confirmed by a doctor to be free of disease

Who may not be able to join:

  • People who do not eat or cannot eat dairy products such as milk, yogurt, cheese, or ice cream
  • People whose body mass index (BMI) falls outside the range of 18.5 to 25, or whose waist measurement is 94 cm or more (for men) or 80 cm or more (for women)
  • People who show signs of mental health conditions based on a structured interview or a depression questionnaire administered by a qualified doctor
  • People with a history of severe psychiatric illness, including major depression, bipolar disorder, schizophrenia, panic disorder, generalised anxiety disorder, post-traumatic stress disorder, agoraphobia, claustrophobia, or certain personality disorders (such as paranoid, schizoid, schizotypal, borderline, or antisocial personality disorder)
  • People with a history of alcoholism or drug dependency
  • People who have previously used antidepressant medication, antipsychotic (neuroleptic) medication, or tranquilisers
  • People who currently smoke, or who have a smoking history of 5 or more "pack years" (a measure combining how much and how long a person smoked)
  • People who are currently taking any prescription or over-the-counter medications, with the exception of birth control
  • People who have worked irregular hours, night shifts, or rotating shifts within the year before the study, or who have travelled across more than one time zone in the three months before the study
  • People with sleep or body-clock disorders, including sleep apnoea, insomnia, narcolepsy, hypersomnia, restless legs-related movement during sleep, REM sleep behaviour disorder, delayed or advanced sleep phase syndrome, or bedwetting (confirm with trial site for specific measurement thresholds)
  • People identified as having an extreme morning or evening body-clock type based on a standard questionnaire (confirm with trial site)
  • People with cardiovascular conditions, including high blood pressure (above 140/90 mmHg), heart failure, heart disease, or a history of heart transplant
  • People who meet the criteria for metabolic syndrome, which involves having excess abdominal fat plus two or more of the following: low HDL ("good") cholesterol, elevated blood pressure, high fasting blood sugar, or high triglycerides (confirm with trial site for specific measurement thresholds)
  • People with pre-diabetes or diabetes, as assessed by fasting blood sugar and, if needed, a haemoglobin A1c blood test
  • People with a current or previous history of beta blocker medication use
  • People with respiratory conditions, including asthma, chronic bronchitis, emphysema, cystic fibrosis, pulmonary hypertension, or lung tumours
  • People with kidney or urinary tract conditions, including kidney failure, a history of kidney transplant, or urinary tract tumours or obstruction
  • People with certain infectious diseases, including HIV, hepatitis, tuberculosis, Lyme disease, sexually transmitted infections, or parasitic infections such as malaria
  • People with gastrointestinal conditions, including inflammatory bowel disease, peptic ulcers, liver disease, cirrhosis, a history of liver transplant, pancreatic disease, or tumours of the digestive system
  • People with immune system or connective tissue disorders, including lupus, rheumatoid arthritis, scleroderma, vasculitis, or sarcoidosis
  • People with blood disorders, including anaemia, leukaemia, or a history of bone marrow transplant
  • People with any cancer or tumour diagnosis, including lymphoma, carcinoma, or melanoma
  • People with endocrine or metabolic conditions, including thyroid disease, Cushing's syndrome, Addison's disease, or disorders affecting the pituitary gland, parathyroid, or bone metabolism
  • People with neurological conditions, including epilepsy, Parkinson's disease, dementia, stroke, multiple sclerosis, muscular dystrophy, Huntington's disease, a history of recurrent migraines, or tumours of the brain or nervous system
  • People who are currently participating in another research study that involves taking experimental medication or giving blood samples

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 20 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Andrew McHill, PhD, Oregon Health and Science University

Phone: 503-494-2594

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Registry
ClinicalTrials.gov
Start date
1 December 2023
Est. completion
30 June 2027

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Circadian Phase; Energy Intake; Energy Content; Glucose Metabolism; Resting energy expenditure; Resting energy macronutrient oxidation; Blood Pressure; Heart Rate; Sympathetic Activity; Parasympathetic Activity; Vascular Endothelial Function; Leptin; Ghrelin; Endocannabinoids; Posture Test Blood Pressure; Posture Test Heart Rate; External Temperature Assessment; Internal Temperature Assessment; Total Energy Expenditure; Changes in Alertness; Measuring Mood with POMS; Measuring Mood with PANAS; Changes in Degrees of Sleepiness; Changes in Sustained Attention and Reaction Time; Changes in Cognit...

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 20 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov