Sleep Disorders Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- People aged 12 to 18 who have been diagnosed with atopic eczema by a Consultant Dermatologist, or healthy individuals without eczema (as a comparison group).
- People with atopic eczema whose condition requires treatment that works through the immune system, or those currently managing eczema with creams or ointments applied to the skin.
- People who have provided written agreement to take part — either signed by the patient themselves, or by a parent or legal guardian, depending on age and understanding.
- People who are willing to follow all the requirements of the study.
- People with a sufficient understanding of English to complete written questionnaires and follow instructions during MRI scans, appropriate to their age.
Who may not be able to join:
- People, or whose parent or guardian, does not sufficiently understand what the study involves.
- People who have any reason they cannot safely have an MRI scan — for example, metal implants or other metal in the body from surgery or injury (a safety questionnaire completed by a radiographer would assess this before any scan takes place).
- People whose ability to complete the MRI parts of the study is limited by a condition such as severe claustrophobia, as determined by the study investigator.
- People who have been diagnosed by a sleep medicine specialist with a formal sleep disorder that requires medication taken by mouth or injection.
- People whose sleep is significantly disrupted by another illness — physical or mental — other than atopic eczema, where the study investigator considers this would meaningfully affect the sleep-related parts of the study.
- People with a past or current history of substance misuse.
- People taking medications that the study investigator believes would affect the quality of the sleep studies.
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
GP referral letter
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Trial details
Where this trial is recruiting
Primary endpoints
Eczema Area and Severity Index (EASI) Score; Peak Pruritus Numerical Rating Score; Transepidermal water loss (TEWL); Skin surface pH; Metabolome swab; Skin ELISA (enzyme-linked immunosorbent assay) and serum ELISA; RNA sequencing of blood serum; Pediatric Sleep Questionnaire; Morningness-Eveningness Questionnaire; Patient-Reported Outcomes Measurement Information System (PROMIS); Pittsburgh Sleep Quality Index; Dreem headband electroencephalogram monitoring; Polysomnography; Actigraphy Watch analysis; EMFIT mattress analysis; Wechsler Abbreviated Scale of Intelligence Second Edition (WASI-II)...
Can't join this trial?
Data last synced from ClinicalTrials.gov: 20 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.