Rheumatoid Arthritis Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People aged 18 years or older
• People who have been diagnosed with rheumatoid arthritis (RA) according to recognised international diagnostic guidelines
• People who have tested positive for certain RA-related antibodies (known as ACPA and/or rheumatoid factor) found in blood tests
• People who have been on a stable RA treatment plan for more than 6 months
• People whose RA is currently in remission or showing low disease activity, as measured by a standard scoring tool called DAS28
• People who are willing to give their consent to take part in the study

Who may not be able to join:

• People who are pregnant or breastfeeding
• People who have used high-dose steroid tablets (more than 30 mg of prednisone per day or a similar amount of another steroid), steroid injections into a vein, biologic therapies, or JAK inhibitor medications in the last 60 days (note: inhaled steroids or local steroid injections into a joint do not automatically exclude someone — confirm with trial site)
• People who have an immune system condition such as HIV, have received an organ transplant, or have another autoimmune disease (other than RA) that requires immune-suppressing treatment
• People who are currently taking systemic steroids at a dose greater than 10 mg of prednisone per day (or equivalent)
• People who have received the medication rituximab or certain chemotherapy drugs within the last 2 years
• People who are expected to need any other cancer treatment during the trial period
• People with a history of blood cancers, primary brain tumours, sarcomas, or other solid tumours, unless they have completed treatment with no sign of the disease for at least 5 years (certain skin cancers and early-stage cancers that were fully removed may be exceptions — confirm with trial site)
• People who are currently taking or have taken antibiotics or antiviral medications within the 3 months before the trial procedure
• People who have an active infection currently requiring treatment, or who were hospitalised for an infection in the last 3 months
• People with a longstanding bowel or intestinal condition such as coeliac disease, inflammatory bowel disease, or a tumour of the colon
• People with certain absolute medical reasons that would make the trial procedure (a stool transplant called FMT) unsafe (confirm with trial site)
• People with a condition called toxic megacolon (a severe bowel condition)
• People with a severe allergic reaction (anaphylaxis) to certain foods such as shellfish, nuts, seafood, or eggs
• People with serious uncontrolled health conditions, including severe heart disease, uncontrolled high blood pressure, serious lung disease, liver cirrhosis or significantly elevated liver enzymes, reduced kidney function, or uncontrolled mental health conditions
• People who have received a live vaccine within 4 weeks before the start of the trial
• People who require insulin to manage their diabetes
• People who have previously had bariatric (weight loss) surgery
• People with a chronic condition causing persistently very low white blood cell counts (neutropenia below 0.5)
• People who are currently participating in another clinical trial

Important: Always verify eligibility with the trial site directly before applying.