Phase 2 Fibromyalgia Trial, Recruiting NCT05900466 Sponsor: University of Utah Condition: Fibromyalgia
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Phase 2 Fibromyalgia Trial, Recruiting

NCT05900466
Recruiting Phase 2

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You are able to read, speak, and understand English well enough to follow the study without an interpreter.
  • You have been diagnosed with Fibromyalgia Syndrome that meets specific official guidelines set by the American College of Rheumatology (from 2016).
  • You are able to swallow a pill and are willing to take a once-daily medication (metformin) as directed throughout the study.

Who may not be able to join:

  • You have a progressive (worsening over time) disease, as diagnosed by a doctor.
  • You have diabetes.
  • You are pregnant or planning to become pregnant within the next year (women who have not yet gone through menopause will be tested for pregnancy).
  • You have a known heart, liver, kidney, or lung condition, as diagnosed by a doctor.
  • You have been diagnosed with certain serious mental health conditions, such as psychosis, or have had recent thoughts of suicide, been admitted to a psychiatric hospital in the past year, engaged in self-harm in the past year, used non-injected drugs in the past two years, or have any history of using recreational drugs intravenously.
  • You have an autoimmune condition (for example, rheumatoid arthritis), as diagnosed by a doctor.
  • You have nerve-related pain (called neuropathic pain), as diagnosed by a doctor.
  • You have pain related to a terminal illness, sudden acute pain, or pain caused by damage to a specific organ (for example, a stomach ulcer), as diagnosed by a doctor.
  • You are currently taking any medications used to control your weight (for example, Xenical/orlistat).
  • You need an interpreter to communicate.
  • Your blood test results show abnormal levels of creatinine (a kidney marker), vitamin B12, or liver function (confirm with trial site).
  • Your kidney filtering rate (a measure of how well your kidneys work) is below a certain level, specifically below 45 mL/min/1.73m² (confirm with trial site).

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 28 July 2026
Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Akiko Okifuji, PhD, University of Utah

Phone: 801-585-7695

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 2
Registry
ClinicalTrials.gov
Start date
1 April 2023
Est. completion
31 March 2027

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Evaluate the safety and efficacy of low-dose metformin in improving the symptoms associated with FMS

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov