Sleep Disorders Trial, Recruiting (NCT05905705)

Sleep Disorders Trial, Recruiting NCT05905705 Sponsor: Washington University School of Medicine Condition: Sleep Disorders

Printed from Voxsanity (voxsanity.com.au) — NCT05905705 — Data sourced from ClinicalTrials.gov. Verify directly with the trial site before attending. Not medical advice.

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Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

People who have been referred for their first course of electroconvulsive therapy (ECT) for depression that has not responded to other treatments, including those with unipolar major depression or bipolar depression
People whose depression is considered treatment-resistant, meaning at least two different antidepressant medications at appropriate doses and for appropriate lengths of time have not worked well enough

Who may not be able to join:

People who have been diagnosed with schizophrenia or schizoaffective disorder
People who are unable to wear the Dreem device (a headband-style sleep monitoring device) during sleep recordings

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.

Last synced 21 July 2026

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: MohammadMehdi Kafashan, Washington University School of Medicine in St. Louis

Phone: 314-273-6129

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Voxsanity

Clinical trials and treatments, explained plainly · voxsanity.com.au

Date:

To: My Doctor

Re: Clinical trial enquiry

I am writing to enquire about the following clinical trial which may be relevant to my care:

Trial: NCT05905705

Sponsor: Washington University School of Medicine

Phase: Not Applicable

Status: Recruiting

Condition: Sleep Disorders

Trial contact: 314-273-6129

More information: https://clinicaltrials.gov/study/NCT05905705

Eligibility summary (AI generated)

Written by an AI model from the ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

People who have been referred for their first course of electroconvulsive therapy (ECT) for depression that has not responded to other treatments, including those with unipolar major depression or bipolar depression
People whose depression is considered treatment-resistant, meaning at least two different antidepressant medications at appropriate doses and for appropriate lengths of time have not worked well enough

Who may not be able to join:

People who have been diagnosed with schizophrenia or schizoaffective disorder
People who are unable to wear the Dreem device (a headband-style sleep monitoring device) during sleep recordings

Important: Always verify eligibility with the trial site directly before applying.

Access in Australia: A treatment being studied in a clinical trial is generally not yet listed on the PBS. Where a medicine is not approved or not available through a trial, the TGA Special Access Scheme may allow a doctor to access unapproved therapeutic goods for individual patients. See voxsanity.com.au/sas-navigator/ for a plain English explainer.

This information was sourced from ClinicalTrials.gov via Voxsanity (data last synced 21 July 2026). It is not medical advice. Please verify the trial's current status directly with the trial site before acting.

Trial details

Status

Recruiting

Phase

Not Applicable

Sponsor

Washington University School of Medicine

Registry

ClinicalTrials.gov

Start date

7 March 2023

Est. completion

31 July 2027

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Slow wave activity (SWA) during non-rapid eye movement sleep (NREM) stage N2/N3; Graph-based neural connectivity measure of local efficiency of information transfer (Elocal) during wakefulness; Graph-based neural connectivity measure of global information transfer (Eglobal) during ECT-induced seizure

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 21 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov