Chronic Rhinosinusitis Trial, Recruiting (NCT05935683)

Chronic Rhinosinusitis Trial, Recruiting NCT05935683 Sponsor: Italian Academy of Rhinology Condition: Chronic Rhinosinusitis

Printed from Voxsanity (voxsanity.com.au) — NCT05935683 — Data sourced from ClinicalTrials.gov. Verify directly with the trial site before attending. Not medical advice.

Back to Chronic Rhinosinusitis

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

You have been diagnosed with Chronic Rhinosinusitis (long-term sinus inflammation) affecting both sides of your nose/sinuses
If you have never had sinus surgery, you meet at least four of the following conditions; if you have had sinus surgery before, you meet at least three of them:
- Blood tests, tissue samples, or nasal tests show signs of a specific type of immune system inflammation (called "type 2 inflammation") involving elevated levels of certain immune cells or proteins (confirm with trial site)
- You have needed at least two courses of steroid tablets/injections, or have been on long-term steroid treatment, for your sinus condition
- Your sinus condition significantly affects your quality of life, based on standard symptom questionnaire scores (confirm with trial site for exact score thresholds)
- You have a severely reduced sense of smell, based on a self-reported scale score

Who may not be able to join:

No specific exclusion criteria were listed in the official trial information (confirm with trial site for any additional restrictions)

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.

Last synced 28 July 2026

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Enrico Marco Heffler, MD, PhD, Personalized Medicine, Asthma and Allergy - IRCCS Humanitas Research Hospital, Rozzano, Italy

Phone: 02 82241

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Voxsanity

Clinical trials and treatments, explained plainly · voxsanity.com.au

Date:

To: My Doctor

Re: Clinical trial enquiry

I am writing to enquire about the following clinical trial which may be relevant to my care:

Trial: NCT05935683

Sponsor: Italian Academy of Rhinology

Phase: Not Applicable

Status: Recruiting

Condition: Chronic Rhinosinusitis

Trial contact: 02 82241

More information: https://clinicaltrials.gov/study/NCT05935683

Eligibility summary (AI generated)

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

You have been diagnosed with Chronic Rhinosinusitis (long-term sinus inflammation) affecting both sides of your nose/sinuses
If you have never had sinus surgery, you meet at least four of the following conditions; if you have had sinus surgery before, you meet at least three of them:
- Blood tests, tissue samples, or nasal tests show signs of a specific type of immune system inflammation (called "type 2 inflammation") involving elevated levels of certain immune cells or proteins (confirm with trial site)
- You have needed at least two courses of steroid tablets/injections, or have been on long-term steroid treatment, for your sinus condition
- Your sinus condition significantly affects your quality of life, based on standard symptom questionnaire scores (confirm with trial site for exact score thresholds)
- You have a severely reduced sense of smell, based on a self-reported scale score

Who may not be able to join:

No specific exclusion criteria were listed in the official trial information (confirm with trial site for any additional restrictions)

Important: Always verify eligibility with the trial site directly before applying.

Access in Australia: A treatment being studied in a clinical trial is generally not yet listed on the PBS. Where a medicine is not approved or not available through a trial, the TGA Special Access Scheme may allow a doctor to access unapproved therapeutic goods for individual patients. See voxsanity.com.au/sas-navigator/ for a plain English explainer.

This information was sourced from ClinicalTrials.gov via Voxsanity (data last synced 28 July 2026). It is not medical advice. Please verify the trial's current status directly with the trial site before acting.

Trial details

Status

Recruiting

Phase

Not Applicable

Sponsor

Italian Academy of Rhinology

Registry

ClinicalTrials.gov

Start date

1 November 2021

Est. completion

31 October 2031

Where this trial is recruiting

🇮🇹 Italy

Primary endpoints

Nasal Polyp Score

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov