Phase 2 Cardiomyopathy Trial, Recruiting NCT05946772 Sponsor: University Hospital Heidelberg Condition: Cardiomyopathy
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Phase 2 Cardiomyopathy Trial, Recruiting

NCT05946772
Recruiting Phase 2

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You are 18 years of age or older
  • You can be enrolled and receive the first dose of the study medication within 24 hours of having a heart catheter procedure
  • Your heart scan (either during the catheter procedure or on ultrasound) showed an abnormal pattern of heart wall movement consistent with a condition called Takotsubo syndrome
  • Your condition scores above a certain level of severity based on two specific medical scoring systems (confirm with trial site)
  • You are able and willing to give written consent to take part

Who may not be able to join:

  • You have been diagnosed with a heart attack or acute heart condition caused by a significant blockage in your coronary arteries, or you have had a procedure to open a blocked artery
  • You currently have an active infection confirmed by a positive blood test at the time of joining the study
  • You have previously had an allergic reaction to a medication called cyclosporine
  • You have previously had an allergic reaction to egg, peanut, or soybean proteins
  • You have a history of serious kidney problems (either poor kidney function based on blood tests, or you are currently receiving medical care for severe kidney disease)
  • You have a history of liver failure or serious liver disease
  • You have very high blood pressure that is not under control at the time of screening for the study
  • You are currently taking any medication containing St. John's Wort, or certain other specific medicines including Stiripentol, Aliskiren, Bosentan, or Rosuvastatin at certain doses (confirm with trial site)
  • You are currently pregnant, or you are a woman who could become pregnant and have not had a negative pregnancy test or are not using effective contraception
  • You have had an immune system disorder in the past 6 months, such as an autoimmune disease, or have tested positive for HIV or hepatitis
  • You are currently receiving treatment that suppresses the immune system, chemotherapy, or antibody-based therapy
  • You are currently taking part in another clinical trial that involves a treatment or intervention (observational studies without any treatment may be acceptable — confirm with trial site)

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 22 July 2026
Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Norbert Frey, MD, University Hospital Heidelberg

Phone: +496221-56-36266

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 2
Sponsor
University Hospital Heidelberg
Registry
ClinicalTrials.gov
Start date
1 February 2025
Est. completion
1 February 2027

Where this trial is recruiting

🇩🇪 Germany

Primary endpoints

Myocardial damage

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 22 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov