Phase 2 Liver Cancer Trial, Recruiting NCT05954897 Sponsor: Guangdong Provincial People's Hospital Condition: Liver Cancer
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Phase 2 Liver Cancer Trial, Recruiting

NCT05954897
Recruiting Phase 2

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People aged 18 years or older.
  • People who have been diagnosed with hepatocellular carcinoma (a type of liver cancer) according to recognised international diagnostic guidelines.
  • People whose liver cancer has been classified as stage C using the Barcelona Clinic Liver Cancer (BCLC) staging system.
  • People who have a main tumour in the liver, with or without a small number of cancer spots that have spread outside the liver — specifically, no more than three spread spots across no more than two other organs, with each spot being no larger than 3 cm.
  • People who have not yet received any treatment for their liver cancer.
  • People who have at least one tumour that can be measured using standard imaging criteria.
  • People who are in good general physical condition, with a performance score of 0 or 1 on the ECOG scale (a medical scale measuring how well a person can carry out daily activities) (confirm with trial site).
  • People whose liver function scores at 7 or below on the Child-Pugh scale, which is a measure of liver health (confirm with trial site).
  • People who are willing to take part voluntarily, sign a consent form, and attend follow-up appointments.
  • People whose blood, liver, and kidney function results meet the required levels set out by the trial (confirm with trial site for specific values).

Who may not be able to join:

  • People whose liver cancer has been confirmed by biopsy to be a specific rare subtype, including fibrolamellar, sarcomatoid, or a mixed liver cancer type.
  • People who have previously had a liver transplant.
  • People who have a history of another type of cancer.
  • People who have a history of severe mental illness.
  • People who have serious uncontrolled complications related to liver disease, such as confusion caused by liver failure, kidney failure linked to liver disease, or uncontrolled fluid build-up in the abdomen, lungs, or around the heart.
  • People who have active bleeding, problems with blood clotting, or who are currently taking blood-thinning or clot-dissolving medications.
  • People who the trial investigators determine are unable to participate for other medical or safety reasons (confirm with trial site).

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 12 July 2026
Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Xiaoming Chen, 106 Second Zhongshan Road, Guangzhou, Guangdong

Phone: +86 15989286619

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 2
Sponsor
Guangdong Provincial People's Hospital
Registry
ClinicalTrials.gov
Start date
1 September 2023
Est. completion
1 January 2026

Where this trial is recruiting

🇨🇳 China

Primary endpoints

Objective Response Rate

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 12 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov