Cardiomyopathy Trial, Recruiting (NCT05965258)

Cardiomyopathy Trial, Recruiting NCT05965258 Sponsor: The Cleveland Clinic Condition: Cardiomyopathy

Printed from Voxsanity (voxsanity.com.au) — NCT05965258 — Data sourced from ClinicalTrials.gov. Verify directly with the trial site before attending. Not medical advice.

Back to Cardiomyopathy

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

Your heart's pumping function (measured by a special heart scan called a cardiac MRI) shows that your heart is pumping at less than 55% of its normal capacity
You have a leaky mitral valve (a valve in your heart) that is at least moderately severe, confirmed by either a cardiac MRI measurement or an ultrasound scan of your heart with clear enough image quality

Who may not be able to join:

You have more than moderate disease of your aortic valve (either leaking or narrowed)
You are under 18 years of age
You currently have acute inflammation of the heart muscle (a condition called myocarditis)
Your kidneys are not working well enough (confirmed by a blood test measuring kidney function below a certain level — confirm with trial site)
You have a condition where the heart muscle is abnormally thick (hypertrophic cardiomyopathy)
You have a condition where abnormal proteins or inflammatory cells have built up in your heart (cardiac amyloidosis or sarcoidosis)
You have previously had any procedure or surgery on your mitral valve
You had a heart attack within 8 weeks before your cardiac MRI scan

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.

Last synced 7 July 2026

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Deborah Kwon, MD, The Cleveland Clinic

Phone: 216-444-8526

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Voxsanity

Clinical trials and treatments, explained plainly · voxsanity.com.au

Date:

To: My Doctor

Re: Clinical trial enquiry

I am writing to enquire about the following clinical trial which may be relevant to my care:

Trial: NCT05965258

Sponsor: The Cleveland Clinic

Phase: Not Applicable

Status: Recruiting

Condition: Cardiomyopathy

Trial contact: 216-444-8526

More information: https://clinicaltrials.gov/study/NCT05965258

Eligibility summary (AI generated)

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

Your heart's pumping function (measured by a special heart scan called a cardiac MRI) shows that your heart is pumping at less than 55% of its normal capacity
You have a leaky mitral valve (a valve in your heart) that is at least moderately severe, confirmed by either a cardiac MRI measurement or an ultrasound scan of your heart with clear enough image quality

Who may not be able to join:

You have more than moderate disease of your aortic valve (either leaking or narrowed)
You are under 18 years of age
You currently have acute inflammation of the heart muscle (a condition called myocarditis)
Your kidneys are not working well enough (confirmed by a blood test measuring kidney function below a certain level — confirm with trial site)
You have a condition where the heart muscle is abnormally thick (hypertrophic cardiomyopathy)
You have a condition where abnormal proteins or inflammatory cells have built up in your heart (cardiac amyloidosis or sarcoidosis)
You have previously had any procedure or surgery on your mitral valve
You had a heart attack within 8 weeks before your cardiac MRI scan

Important: Always verify eligibility with the trial site directly before applying.

Access in Australia: A treatment being studied in a clinical trial is generally not yet listed on the PBS. Where a medicine is not approved or not available through a trial, the TGA Special Access Scheme may allow a doctor to access unapproved therapeutic goods for individual patients. See voxsanity.com.au/sas-navigator/ for a plain English explainer.

This information was sourced from ClinicalTrials.gov via Voxsanity (data last synced 7 July 2026). It is not medical advice. Please verify the trial's current status directly with the trial site before acting.

Trial details

Status

Recruiting

Phase

Not Applicable

Sponsor

The Cleveland Clinic

Registry

ClinicalTrials.gov

Start date

29 August 2023

Est. completion

31 December 2028

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Composite of cardiac mortality, heart transplant, or LVAD implantation.

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 7 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov