Liver Cancer Trial, Recruiting

Written by an AI model from the ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People aged between 18 and 75 years
• People who have been diagnosed with hepatocellular carcinoma (a type of liver cancer), confirmed by imaging, tissue sample, or cell testing
• People whose liver cancer has spread into a specific part of a major liver blood vessel, classified as Type I or Type II (confirm with trial site for exact classification)
• People whose liver is functioning at a level doctors classify as "Child-Pugh class A" (a measure of liver health — confirm with trial site)
• People who are largely able to carry out daily activities, with little or no limitation due to illness (rated 0 or 1 on a standard medical scale)
• People who have not previously received any systemic (whole-body) drug treatment for their liver cancer
• People whose blood counts and organ function meet minimum health thresholds set by the trial (confirm with trial site for specific values)
• People who have at least one measurable tumour in the liver that can be tracked during the trial

Who may not be able to join:

• People whose liver cancer is spread diffusely throughout the liver rather than in defined tumours
• People whose liver cancer is a specific subtype, including cholangiocarcinoma, fibrolamellar, sarcomatoid, or mixed hepatocellular/cholangiocarcinoma, confirmed by tissue testing
• People whose cancer has spread to areas outside the liver
• People for whom the trial's treatment procedures would be medically inadvisable, as determined by the trial doctors
• People who have a history of serious bleeding events (above a certain severity level) in the four weeks before joining the trial
• People with an active or past autoimmune disease or a condition affecting the immune system
• People with untreated or incompletely treated enlarged veins in the oesophagus or stomach that are bleeding or carry a high risk of bleeding
• People who had a bleeding event from oesophageal or stomach varices within the six months before starting the trial
• People with evidence of significant blood clotting problems or difficulty controlling bleeding
• People who are pregnant or breastfeeding
• People with significant heart or cardiovascular disease
• People with a severe active infection, such as active tuberculosis
• People with serious ongoing medical conditions (confirm with trial site for specifics)
• People who have previously had an organ or cell transplant
• People who have another cancer that is not curable

Important: Always verify eligibility with the trial site directly before applying.