Sleep Disorders Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People aged between 55 and 85 years old
• People whose thinking and memory are considered normal, based on a cognitive screening test score of 29 or higher
• People who have moderate to severe sleep apnea, confirmed by a sleep test taken within the past 12 months (or confirmed by a repeat test)
• People who are not currently being treated for sleep apnea, and have not received any sleep apnea treatment for at least 6 months
• People who are willing and able to receive treatment for sleep apnea as part of the trial
• People who speak English or Spanish fluently

Who may not be able to join:

• People who have been diagnosed with chronic insomnia, or who report severe or very severe difficulty falling asleep on a screening questionnaire
• People who have been diagnosed with a circadian rhythm disorder (a condition where the body's internal clock is significantly disrupted)
• People who currently use supplemental oxygen
• People who have another type of sleep-related breathing disorder, such as central sleep apnea
• People who currently work night shifts (regularly working between 12am and 6am) or have done so in the past 6 months
• People who have bariatric (weight loss) surgery planned within the next 3 months
• People who regularly use cannabis to help with sleep more than 2 nights per week
• People who have an uncontrolled psychiatric condition diagnosed in the last 6 months, or a history of schizophrenia or bipolar disorder (confirm with trial site for details on which conditions may still be considered)
• People taking methylphenidate (a medication used for ADHD), unless the dose has been stable for some time — the trial's lead doctor would review this on a case-by-case basis
• People taking certain weight-loss medications (such as Ozempic, Wegovy, Rybelsus, Mounjaro, or Zepbound) who are also planning to lose 20 pounds or more at the time of joining the trial — the trial's lead doctor would review this individually
• People with serious ongoing health conditions that would make it difficult to complete the study over 2 years, or that could affect thinking and memory (confirm with trial site for specific conditions)
• People who do not sleep in the same place most nights (sleeping in a different location more than 2 nights per week)
• People who are currently pregnant or planning to become pregnant
• People who have been diagnosed with a brain or nervous system condition such as multiple sclerosis, stroke, Parkinson's disease, Alzheimer's disease, epilepsy, traumatic brain injury, or who have experienced a loss of consciousness lasting more than 24 hours — or who have experienced delirium in the past 12 months
• People who have had a near-miss or actual car accident caused by sleepiness in the past 12 months
• People who work as commercial drivers (such as bus drivers, train operators, or airline pilots) during the study period
• People who currently take neuroleptics, benzodiazepines, barbiturates, opiates, or anti-amyloid therapies (certain types of psychiatric, sedative, pain, or dementia-related medications)
• People taking cognitive-enhancing medications that were started within the last 3 months, or where the dose is not yet stable
• People who drink more than 14 alcoholic drinks per week, unless their drinking has been reduced and stabilised within the past 3 months

Important: Always verify eligibility with the trial site directly before applying.