Phase 2 Liver Cancer Trial, Recruiting NCT05992220 Sponsor: Asan Medical Center Condition: Liver Cancer
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Phase 2 Liver Cancer Trial, Recruiting

NCT05992220
Recruiting Phase 2

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who are between 19 and 80 years of age
  • People whose liver is functioning at a level doctors classify as "Child-Pugh class A" (a measure of liver health — confirm with trial site)
  • People whose general physical health and ability to carry out daily activities is rated as good to fully active (ECOG performance score of 0 or 1 — confirm with trial site)
  • People diagnosed with liver cancer (HCC) that has grown into the blood vessels inside the liver, diagnosed according to standard medical guidelines
  • People who have not yet received any systemic (whole-body) treatment for their liver cancer
  • People who have at least one measurable liver cancer lesion that is 1 cm or larger
  • People whose blood counts and organ function meet the following levels: haemoglobin at least 9.0 g/dL, neutrophil count at least 1,000 per mm³, and platelet count at least 50,000 per mm³ without needing a transfusion
  • People whose total bilirubin (a liver marker in the blood) is at or below 2.5 mg/dL

Who may not be able to join:

  • People who have previously received systemic (whole-body) treatment for liver cancer
  • People who have had a liver transplant
  • People with peptic ulcers, or with varices (enlarged veins, often in the digestive tract) that are untreated, incompletely treated, currently bleeding, or at high risk of bleeding
  • People with any serious illness, active infection, active inflammatory condition, or a severe ongoing medical condition that is not well controlled
  • People with a history of another cancer (other than liver cancer), unless that cancer has been in complete remission for at least two years, with no chemotherapy and no additional surgery during that time
  • People who have had radiation therapy to the abdomen or pelvis within the 28 days before starting the study treatment (an exception may apply for palliative radiation to bone lesions within 7 days before starting — confirm with trial site)

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 21 July 2026
Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Ju Hyun Shim, Asan Medical Center

Phone: 82-31-560-2209

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 2
Registry
ClinicalTrials.gov
Start date
22 October 2022
Est. completion
1 March 2026

Where this trial is recruiting

🇰🇷 South Korea

Primary endpoints

progression-free survival rate

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 21 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov