Heart Disease Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People aged 19 years or older.
• People who have a specific type of blocked artery at a branching point in the heart, where the branch vessel measures between 2.25 and 2.75 mm wide, the main vessel is at least 2.5 mm wide, and the blockage meets a specific pattern called a "true bifurcation" (Medina classification 1,1,1), (1,0,1), or (0,1,1) — this is a new blockage, not a previously treated one (confirm with trial site).
• People whose heart condition is diagnosed as stable chest pain (stable angina), unstable chest pain (unstable angina), or a certain type of heart attack (non-ST elevation myocardial infarction), at least 24 hours after their last treatment for that condition.
• People who have been fully informed about the trial, understand the risks involved, and have given their written consent to participate — either personally or through a legal representative.

Who may not be able to join:

• People who have had a specific type of serious heart attack (ST-elevation myocardial infarction), or who have a true bifurcation blockage in the left main coronary artery.
• People whose treating doctor has decided that a two-stent procedure is not appropriate for their condition.
• People who cannot take aspirin or certain blood-thinning medications called P2Y12 inhibitors (such as ticagrelor or clopidogrel) due to a medical contraindication.
• People who experienced severe circulatory collapse (cardiogenic shock) at hospital admission, or who have significantly reduced heart pumping function (left ventricle ejection fraction below 30%).
• People who need to take long-term blood-thinning medication, such as warfarin or a newer oral anticoagulant (NOAC).
• People who are currently bleeding, or who are considered at high risk of serious bleeding (for example, due to active stomach ulcers, certain digestive tract conditions, or tumours with a high bleeding risk).
• People with a history of bleeding in the brain or a brain aneurysm.
• People who have a surgical procedure planned within the next six months that would require stopping blood-thinning medication.
• People with severe liver disease (including fluid build-up in the abdomen), a very low platelet count (below 80,000 cells/mm³), or a low haemoglobin level (below 10 g/dL).
• People considered at risk of an abnormally slow heart rate, including those with a significant heart rhythm conduction problem (grade 2 or higher atrioventricular block) who do not have a permanent pacemaker.
• People who are pregnant (based on a positive pregnancy test) or currently breastfeeding.
• People whose doctor estimates they have less than one year of life expectancy due to other serious health conditions.
• People who are already taking part in another clinical trial for a different medicine or medical device, where the main study results have not yet been collected.
• People who have not signed an informed consent form, or who cannot be reliably followed up over the long term.

Important: Always verify eligibility with the trial site directly before applying.