HIV and AIDS Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People who have a confirmed HIV diagnosis
• People who describe themselves as not very physically active — specifically, those who do less than 3 days per week of activity that makes them sweat, and who have not done regular strength/resistance exercise in the past 3 months
• People who experience fatigue, based on a score of 2.0 or higher on the first two questions of a standard HIV-related fatigue questionnaire
• People who have been on a current HIV treatment (antiretroviral therapy) regimen for at least 12 months
• People whose HIV viral load has been below 200 copies/mL in the past 12 months, as shown in their medical records
• People who are willing to attend a supervised exercise program 3 times per week for 4 months
• People who have access to a cell phone or email to receive messages
• People who weigh less than 450 pounds
• People who have received medical clearance from the study's healthcare professional

Who may not be able to join:

• People who weigh more than 450 pounds
• People who have been taking sex hormone therapy for 3 months or less (those who have been on a stable dose for more than 3 months may still be considered)
• People who have been taking other hormone replacement therapy for 3 months or less (those who have been on a stable dose for more than 3 months may still be considered)
• People with anaemia — specifically, low haemoglobin levels (below 9 g/dL for women or below 10 g/dL for men)
• People who have been diagnosed with a mitochondrial disease
• People with active substance use issues, or other factors that the trial site's investigator believes could affect their safety or ability to complete study visits
• People with high blood pressure that is not well controlled — specifically, a resting blood pressure reading above 150/90 mmHg (those who do not meet this at first screening may be re-evaluated after follow-up with their own doctor)
• People with unstable heart disease, such as chest pain (angina) or abnormal heart rhythms detected at rest or during an exercise test, without a follow-up evaluation clearing them
• People with more advanced heart failure (classified as New York Heart Association Class III or IV), significant narrowing of the aortic heart valve, or heart rhythm problems that are not well controlled
• People with a lung condition that requires them to use supplemental oxygen either at rest or during physical activity
• People who have received chemotherapy or radiation therapy for cancer within the past 24 weeks
• People with poorly controlled diabetes, shown by a blood sugar marker (HbA1c) above 8.5 within the past 6 months, or who are currently using insulin
• People who have had surgery, a significant injury, or a bone fracture within the past 24 weeks that the study clinician believes could affect their ability to exercise or complete baseline testing
• People who have balance problems that could affect their ability to safely exercise or complete functional testing, either reported by the person themselves or noted in their medical records
• People with significant joint or bone problems — such as severe osteoarthritis or rheumatoid arthritis — that greatly limit their ability to do moderate-level strength exercises
• People whose overall health the study clinician considers to be unstable, or who the clinician believes cannot safely take part in the exercise program

Important: Always verify eligibility with the trial site directly before applying.