Printed from Voxsanity (voxsanity.com.au) — NCT06029114 — Data sourced from ClinicalTrials.gov. Verify directly with the trial site before attending. Not medical advice.
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Alzheimer's Disease Trial, By Invitation
NCT06029114
voxsanity.com.au · Eligibility summary from public government registries · 18 August 2026 · not medical advice
Who may and may not be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who may be able to join
- People who are in good general health.
- People who have no active neurological or psychiatric conditions, or who had a past neurological or psychiatric condition but have fully returned to normal health.
- People who have no complaints about their memory or thinking ability (for the healthy comparison group).
- People whose neurological examination results are normal.
- People who are not taking any medications that affect mood, thinking, or behaviour.
- People who may have an ongoing medical condition, as long as it does not affect thinking or memory.
- People whose brain scan shows a low level of amyloid protein buildup (a PiB ratio below 1.5) — this applies to the healthy comparison group.
- People who have noticed memory problems, with those concerns also confirmed by someone who knows them well (for the mild memory decline group).
- People whose general thinking and mental abilities are within the normal range, as measured by standard tests (for the mild memory decline group).
- People whose ability to carry out everyday activities is normal, based on their history and a standard assessment (for the mild memory decline group).
- People who do not meet the criteria for dementia based on standard diagnostic guidelines (DSM-III-R) (for the mild memory decline group).
- People who have a measurable memory problem as assessed by specialist neuropsychologists and neurologists (for the mild memory decline group).
- People whose brain scan shows a high level of amyloid protein buildup (a PiB ratio of 1.5 or above) — this applies to both the mild memory decline group and the dementia group.
- People whose dementia is not caused by another medical or psychiatric condition (for the dementia group).
- People who have been diagnosed with dementia according to standard diagnostic guidelines (DSM-III-R) (for the dementia group).
- People who have a measurable memory problem as assessed by specialist neuropsychologists and neurologists (for the dementia group).
Who may not be able to join
Each point below is a reason the trial team may not be able to accept someone. It is not a list of requirements to meet.
- People whose Alzheimer's disease or mild cognitive impairment is linked to a known genetic mutation.
- People who have major depression.
- People with a history of a brain tumour (primary or that has spread from elsewhere), significant head injury, bleeding within the brain, or a stroke affecting a large part of the brain.
- People for whom MRI scanning is not safe, including those with a cardiac pacemaker, metal in or around the eye or brain, or other devices that are not compatible with MRI machines.
- Women who are pregnant, or women who could become pregnant and receive a positive urine pregnancy test before the MRI scan, will not be included in the study.
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
GP referral letter
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Trial details
Status
By Invitation
Phase
Not Applicable
Sponsor
Registry
ClinicalTrials.gov
Start date
11 October 2023
Est. completion
1 November 2027
Where this trial is recruiting
🇺🇸 United States
Primary endpoints
Shear Stiffness
Can't join this trial?
Data last synced from ClinicalTrials.gov: 12 August 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.
Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.