Early Phase 1 Sleep Disorders Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• You are between 18 and 70 years old
• You are willing to sign a consent form and follow all study requirements for the full duration of the trial
• You own a smartphone (iPhone or Android)
• You currently eat across a window of 12 hours or more per day, and are able to log your eating using the myCircadianClock app
• You have been diagnosed with moderate to severe obstructive sleep apnea (a sleep condition where breathing repeatedly stops during sleep) that is not currently being treated
• If you take certain heart or cholesterol medications (such as statins, other cholesterol-lowering drugs, or blood pressure medications), you agree not to change your dose during the study
• You agree to follow the lifestyle guidelines set out by the study for its full duration

Who may not be able to join:

• You have type 1 or type 2 diabetes and take insulin or sulfonylurea medications, or you have ever had a low blood sugar episode without being aware of it
• You have sleep apnea and also experience significant daytime sleepiness, either scoring 15 or higher on a standard sleepiness questionnaire, or having been in a car accident due to excessive sleepiness in the past year
• Your BMI (a measure of body weight relative to height) is over 40
• You have high blood pressure that is not well controlled
• You currently smoke or use illicit drugs
• You are pregnant or breastfeeding
• You are currently taking part in a weight-loss or weight-management program
• You are currently following a special or medically prescribed diet (for example, for Celiac disease)
• You are currently taking any medication intended for weight loss or known to reduce appetite
• You have a history of an eating disorder
• You have previously had surgery for weight management
• You have chronic kidney disease
• You are currently being treated for an active inflammatory condition, rheumatologic (joint/immune) disease, or cancer
• You have heart or artery disease that has not been treated with a procedure to restore blood flow
• You have liver cirrhosis or significantly abnormal liver function
• You have a thyroid condition that required a change in your thyroid medication dose within the past 3 months (note: having hypothyroidism on a stable, unchanged dose does not exclude you — confirm with trial site)
• You work shift work with variable hours, including occasional night shifts
• You are planning to travel outside the United States during the study
• You have a history of HIV/AIDS
• You have a psychiatric condition that is not well controlled
• A study doctor has another safety concern about your participation

Important: Always verify eligibility with the trial site directly before applying.