Phase 2 Liver Cancer Trial, Recruiting NCT06166576 Sponsor: Seoul National University Hospital Condition: Liver Cancer
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Phase 2 Liver Cancer Trial, Recruiting

NCT06166576
Recruiting Phase 2

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • Adults aged 18 or older
  • People diagnosed with liver cancer (hepatocellular carcinoma) that is located in only one lobe of the liver, confirmed by tissue sample and/or imaging scans
  • People who have at least one liver tumour larger than 10 mm that can be measured on a specialised CT or MRI scan
  • People whose cancer has grown into a nearby blood vessel (portal vein) only within one lobe of the liver, as seen on a specialised CT or MRI scan
  • People with no signs of cancer that has spread outside the liver, based on a chest CT and abdominal CT or MRI scan
  • People who have not previously received any treatment for their liver cancer
  • People whose liver is functioning at a level known as Child-Pugh class A (confirm with trial site)
  • People whose general physical functioning is rated as 0 or 1 on a standard medical scale, meaning they are fully active or have only minor limitations in physical activity
  • People whose recent blood tests (taken within one month of joining the study) show that major organs such as the liver, kidneys, and bone marrow are working within acceptable ranges
  • People with a life expectancy of more than 3 months
  • People who have read, understood, and signed a written consent form for the trial
  • Women of childbearing age who have been confirmed as not pregnant

Who may not be able to join:

  • People whose pre-treatment scan (using a special substance called 99mTc-MAA) shows that the planned radiation treatment would deliver too high a dose to the lungs or to the healthy part of the liver in the opposite lobe
  • People where the volume of healthy, untreated liver tissue makes up less than 30% of their total healthy liver volume
  • People whose cancer has spread into the liver's major veins or bile ducts, as seen on a specialised CT or MRI scan
  • People who are planned to receive immunotherapy, regardless of how their liver cancer responds to the trial treatment
  • People who had another active cancer at any point in the two years before joining the trial
  • People who have previously had surgery or procedures involving the bile ducts
  • Women who are pregnant or breastfeeding

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 9 July 2026
Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Jin Woo Choi, MD, PhD, Seoul National University Hospital

Phone: +82-220722584

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 2
Registry
ClinicalTrials.gov
Start date
20 November 2023
Est. completion
30 November 2027

Where this trial is recruiting

🇰🇷 South Korea

Primary endpoints

Overall survival

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 9 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov