Phase 4 Heart Disease Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- Adults aged 18 or older
- People admitted to hospital with a diagnosis of acute heart failure where the body is retaining excess fluid
- People showing signs that their water tablets (diuretics) may not be working well enough, which means either having taken daily diuretics by mouth for at least 7 days before admission, or not losing enough fluid in the past 24 hours (less than 500g in weight or less than 1 litre of fluid) despite receiving high doses of diuretics through a drip
- People showing physical signs of excess fluid buildup, such as swelling in the legs or ankles, fluid in the abdomen, raised pressure in the neck veins, or scan results showing fluid on the lungs
Who may not be able to join:
- People who are having an acute heart attack or acute coronary syndrome
- People whose systolic blood pressure (the top number) is below 85 mmHg
- People who have already received kidney dialysis or a fluid-removal procedure (ultrafiltration) during the current hospital stay before the study begins
- People who have already been treated with acetazolamide or metolazone (specific types of diuretic medications) during the current hospital stay before being enrolled in the trial
- People with a known allergy to any of the medications used in the trial
- People with severely low potassium or severely low sodium levels in their blood
- People with severe liver disease or liver cirrhosis
- People who are known to be pregnant
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Johannes Grand, MD, Phd, MPH, Amager-Hvidovre Hospital
Phone: +4535452121
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Days alive out-of-hospital to day 30
Can't join this trial?
Data last synced from ClinicalTrials.gov: 14 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.