Sleep Disorders Trial, Recruiting NCT06189755 Sponsor: University of Pennsylvania Condition: Sleep Disorders
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Sleep Disorders Trial, Recruiting

NCT06189755
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

If you have sleep apnea (Cases):

  • You are between 18 and 75 years old
  • You have been diagnosed with moderate to severe sleep apnea (meaning your breathing stops or becomes shallow at least 15 times per hour during sleep)
  • You are willing to use a PAP machine (a breathing device worn during sleep) as part of the trial

If you do not have sleep apnea (Controls):

  • You are between 18 and 75 years old
  • You have been confirmed to not have sleep apnea (fewer than 5 breathing disruptions per hour during sleep)

Who may not be able to join:

If you have sleep apnea (Cases):

  • You are currently using a PAP machine or any other treatment for sleep apnea
  • You currently use oxygen at home
  • Your blood pressure medications have been changed in the last 3 months
  • Your sleep study showed a specific unusual breathing pattern called Cheyne-Stokes Respiration (confirm with trial site)
  • Your sleep apnea is mainly caused by signals from the brain rather than a physical blockage (confirm with trial site)
  • You are pregnant
  • You have severe kidney disease that requires dialysis or you have had a kidney transplant
  • You have had any organ transplant
  • You regularly sleep less than 5 hours on weeknights
  • You currently work night shifts

If you do not have sleep apnea (Controls):

  • You currently use oxygen at home
  • You are pregnant
  • You have severe kidney disease that requires dialysis or you have had a kidney transplant
  • You have had any organ transplant
  • You regularly sleep less than 5 hours on weeknights
  • You currently work night shifts

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 23 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Allan I Pack, MBChB, PhD, University of Pennsylvania

Phone: 215-614-0047

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Registry
ClinicalTrials.gov
Start date
1 April 2024
Est. completion
1 November 2027

Where this trial is recruiting

Iceland 🇺🇸 United States

Primary endpoints

microRNA

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 23 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov