Liver Cancer Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People aged 18 to 75 years old who have liver cancer or other liver tumours and are scheduled for a keyhole (laparoscopic) liver removal surgery that targets a specific section of the liver
• People whose liver is functioning at a level rated as Grade A or B on a standard medical scoring system called Child-Pugh
• People who have no medical reasons preventing them from having keyhole liver surgery
• People whose life expectancy is at least 3 months
• People who are generally well enough to carry out light activity, rated 0 or 1 on a standard health performance scale (ECOG PS)
• People whose major organs are working well and whose recent blood test results (taken within 7 days before joining) meet specific minimum levels for white blood cells, infection-fighting cells, platelets, haemoglobin, kidney function, and liver markers
• People who are willing to take part and have signed a consent form

Who may not be able to join:

• People in whom, during surgery, the targeted part of the liver does not show a clear boundary after blood supply is blocked, or whose liver already glows too brightly before a special dye (ICG) is injected during the procedure
• People whose liver has poor reserve capacity, measured by a specific liver function test (ICG R15 of 20% or more)
• People with serious heart or lung conditions that mean they cannot safely have a general anaesthetic or surgery
• People with a moderate or large amount of fluid build-up in the abdomen or around the lungs that is causing symptoms
• People who have active bleeding or problems with blood clotting
• People who have a condition where the liver is not filtering toxins properly, affecting brain function (hepatic encephalopathy)
• People who are allergic to the dye ICG
• People who have had bleeding in the stomach or digestive tract in the past 6 months, or who have a clear risk of this happening
• People with severely enlarged veins in the oesophagus or stomach that need medical treatment
• People with clear evidence of severely reduced lung function, such as pulmonary fibrosis
• People with any significant health or test result abnormalities that the trial doctors believe could affect the safety of the study

Important: Always verify eligibility with the trial site directly before applying.