Phase 1 Cardiomyopathy Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- You have a specific gene change (mutation) in the PKP2 gene that is known or likely to cause disease
- You have been diagnosed with a heart condition called Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC), based on specific medical guidelines from 2010
- Your heart's pumping strength (specifically the left side of your heart) is at 50% or above, meaning it is pumping normally or near-normally
- You have had a working implantable defibrillator (a device in your chest that can shock your heart back into a normal rhythm) for at least 9 months before the study starts, and it can send data remotely
- Your heart failure symptoms are mild to moderate — you are in functional class I, II, or III (meaning you can carry out at least some daily activities)
- You experience frequent irregular heartbeats that start in the lower chambers of your heart (called premature ventricular contractions, or PVCs)
Who may not be able to join:
- You have had a procedure to treat dangerous heart rhythm problems (ventricular tachycardia ablation) within the last 6 months, or one is planned within the next 6 months
- You have high levels of a certain antibody in your blood that could interfere with the treatment being studied (confirm with trial site)
- You have previously had a heart attack
- You have heart failure specifically affecting the right side of your heart
- Your heart failure is at the most severe level (Class IV), meaning you have symptoms even at rest
- You have a serious kidney condition
- You have a serious liver condition
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Phone: (650) 416-1186
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Number and severity of Adverse Events over the course of the study.; Number of Serious Adverse Events related to study drug.
Can't join this trial?
Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.