Rheumatoid Arthritis Trial, Recruiting NCT06246123 Sponsor: Eisai Korea Inc. Condition: Rheumatoid Arthritis
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Rheumatoid Arthritis Trial, Recruiting

NCT06246123
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You are currently being prescribed Jyseleca (filgotinib) tablets in South Korea, following the approved guidelines for its use there.
  • You have moderate to severe rheumatoid arthritis as an adult, and previous treatments (called DMARDs) have not worked well enough for you or caused side effects you could not tolerate.
  • You have moderate to severe ulcerative colitis as an adult, and previous treatments (such as steroids, immune-suppressing medicines, or biological medicines) have not worked, stopped working, or caused side effects you could not tolerate.
  • If you are over 65, have a high risk of heart disease, or have a history of cancer, you may still be considered, but only if other treatments have not worked or have not been tolerated (confirm with trial site).

Who may not be able to join:

  • You have a known allergy or sensitivity to any ingredient in the Jyseleca tablet.
  • You currently have an active infection of any kind, including serious infections like blood poisoning (sepsis), or a local infection.
  • You currently have active tuberculosis (TB).
  • You have severe liver disease.
  • You have end-stage kidney disease (kidneys that are failing completely).
  • Your blood test results show that certain blood cell levels are too low — specifically, your white blood cells (neutrophils), immune cells (lymphocytes), or red blood cells (haemoglobin) fall below certain limits (confirm exact values with trial site).
  • You are pregnant, possibly pregnant, or currently breastfeeding.
  • You have certain rare inherited conditions affecting how your body handles sugars, such as galactose intolerance or glucose-galactose malabsorption, because the tablet contains lactose.
  • You are already taking part in another clinical study involving filgotinib (the active ingredient in Jyseleca).
  • The doctor running the trial considers your participation unsuitable for any other medical reason.

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 22 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Phone: +82-2-3451-5533

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
Eisai Korea Inc.
Registry
ClinicalTrials.gov
Start date
27 February 2024
Est. completion
30 July 2027

Where this trial is recruiting

🇰🇷 South Korea

Primary endpoints

Number of Participants With Serious Adverse Events (SAEs); Number of Participants With Adverse Drug Reactions (ADRs); Number of Participants With Unexpected AEs; Number of Participants With Unexpected ADRs; Number of Participants With Known ADRs; Number of Participants With Non-serious AEs; Number of Participants With Non-serious ADRs; Change From Baseline in Disease Activity Score 28 Based on C-Reactive Protein (DAS28-CRP) at Week 12 and Week 24; Change From Baseline in the Mayo Clinic Score (MCS) at Week 12 and Week 24

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 22 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov