Phase 2 Sleep Disorders Trial, Recruiting

Written by an AI model from the ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People who are able to give informed consent to participate
• People who are 25 years of age or older at the first study visit
• People who have been diagnosed with any type of solid tumour and who are currently receiving, or have received in the past 18 months, treatment aimed at either curing the cancer or managing its symptoms
• People who are currently experiencing sleep problems, pain, and/or mood difficulties such as depression or anxiety
• People who wish to use cannabis to help manage their symptoms
• People who have not been using cannabis products regularly (more than 3 times per month) in the past 6 months
• People who are willing to use an acceptable form of birth control for the duration of the study

Who may not be able to join:

• People who have used illegal drugs such as cocaine or methamphetamine in the past 90 days
• People who are currently taking anti-epilepsy medications (such as clobazam, sodium valproate, or lamotrigine)
• People who are currently taking certain medications known to interact with the study drug Epidiolex (such as buprenorphine, sodium oxybate, or lomitapide — confirm full list with trial site)
• People who are currently taking anti-psychotic medications
• People who are currently taking certain medications that strongly affect how the body processes drugs, including rifampin, carbamazepine, phenytoin, St. John's wort, or phenobarbital (confirm full list with trial site)
• People whose liver enzyme levels (ALT and AST) are significantly elevated above the normal range
• People who have moderate or severe liver disease
• People who have a personal or family history of psychosis, or who currently have a major psychiatric condition such as bipolar disorder, major depression, or schizophrenia
• People who have a history of seizures
• Women who are pregnant, breastfeeding, or trying to become pregnant during the study period; women of childbearing potential who do not have confirmed inability to become pregnant through menopause or surgical procedure (confirm details with trial site)
• People whose treating doctor has indicated that participation in the trial would not be appropriate for them
• People who are unwilling to avoid using cannabis products other than the study drug for the full duration of the study
• Men who drink more than 2 alcoholic beverages per day, or women who drink more than 1 alcoholic beverage per day

Important: Always verify eligibility with the trial site directly before applying.