Cardiomyopathy Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People who are between 14 and 65 years old at the time of signing consent
• People who have a confirmed harmful or likely harmful change (mutation) in the PKP2 gene
• People who have been diagnosed with a heart condition called ARVC, meeting a specific set of diagnostic guidelines known as the 2010 Modified Task Force Criteria
• People who have a working implanted heart device (ICD) already in place

Who may not be able to join:

• People who are currently taking medicines that suppress the immune system, chemotherapy drugs, immunoglobulin therapy, or monoclonal antibody treatments
• People who have a history of significant liver disease, hepatitis B, hepatitis C, HIV, or tuberculosis
• People who have previously received any gene therapy product, whether as part of a trial or as an approved treatment
• People who are already taking part in another clinical trial that involves a treatment or intervention, unless the trial sponsor has given specific approval (participation in observation-only studies may be considered at the doctor's discretion)
• People who have had a heart transplant at any point in the past

Important: Always verify eligibility with the trial site directly before applying.