Heart Disease Trial, Recruiting NCT06338696 Sponsor: Mahidol University Condition: Heart Disease
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Heart Disease Trial, Recruiting

NCT06338696
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You must be older than 18 years of age.
  • You must have been diagnosed with a condition called ATTR cardiomyopathy (a disease where a protein called transthyretin builds up in the heart), whether or not you currently have symptoms.
  • Your heart must show signs of involvement on an ultrasound scan (echocardiogram), specifically that the heart wall is thicker than normal (12mm or more).
  • You must also meet at least ONE of the following conditions:
    • A special bone scan (using a radioactive tracer) showed a strong positive result for protein buildup in the heart.
    • A special bone scan showed a mildly positive result, AND a heart tissue sample (biopsy) taken from at least 4 sites confirmed the diagnosis using a special staining method.
    • A special bone scan showed a mildly positive result, AND a tissue sample taken from somewhere other than the heart confirmed the diagnosis using a special staining method.
    • A heart MRI scan showed certain abnormal patterns, AND a tissue sample (from the heart or elsewhere in the body) confirmed the diagnosis using a special staining method (confirm with trial site for specific MRI findings).

Who may not be able to join:

  • You have been diagnosed with a type of amyloidosis caused by a different protein (for example, a type called light chain amyloidosis), not the transthyretin protein.
  • You have been diagnosed with a type of amyloidosis that developed as a result of another condition (called secondary amyloidosis).

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 26 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Rungroj Krittayaphong, MD, FESC, FACC, Division of Cardiology, Department of Medicine, Siriraj Hospital, Mahidol University

Phone: 0635153519

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
Mahidol University
Registry
ClinicalTrials.gov
Start date
30 July 2024
Est. completion
1 June 2029

Where this trial is recruiting

🇹🇭 Thailand

Primary endpoints

Rate of death; Rate of heart failure hospitalization

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 26 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov