Phase 4 HIV and AIDS Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

People living with HIV (PLWH):

• People who are 18 years of age or older at the time of signing the consent form
• People who speak English
• People who are able to understand and follow the study requirements, as assessed by the clinic or study team
• People who have a confirmed HIV-1 diagnosis, shown by a positive HIV test or detectable HIV in the blood
• People who have been out of HIV care, meaning they have not seen an HIV care provider in 6 months or more, and have not been taking HIV treatment for at least 1 month (based on what they report themselves)

Site staff (healthcare and administrative workers):

• People who are 18 years of age or older at the time of signing the consent form
• People who work at a participating site as HIV care providers, case managers, pharmacists, or administrators involved in the study's clinical or administrative activities
• People who understand the long-term commitment the study requires and are willing to take part
• People who have enough time and resources to complete study assessments for the full duration of the study

Who may not be able to join:

People living with HIV (PLWH):

• People for whom the study medication Biktarvy (B/F/TAF) is not recommended or is not safe, including:
  • People with a known history of significant kidney disease (with kidney function below a certain level) who are not on dialysis
  • People with a known allergy to any ingredient in Biktarvy
  • People whose medical records show a significant level of resistance to Biktarvy's components based on a drug resistance test (note: not having had a resistance test before, or having a specific common mutation called M184V/I, does not automatically exclude someone — confirm with trial site)
  • People currently taking other medications that are known to interact dangerously with Biktarvy, as determined by recognised drug interaction references
  • People who are pregnant (by their own report) or planning to become pregnant during the study
• People who have HIV-2 (rather than HIV-1)
• People who are breastfeeding and are either not on HIV treatment, or are on HIV treatment but the virus is not fully suppressed
• People who have a serious active infection that, according to their HIV care provider and current medical guidelines, would mean HIV treatment needs to be delayed — examples include certain types of meningitis or a specific eye infection called CMV retinitis
• People who do not live in the state of Missouri at the time of the study, or who are planning to move away during the study period
• People who are incarcerated at the time of enrolling in the study

Site staff:

• People who are planning to move their place of work or change jobs within one year

Important: Always verify eligibility with the trial site directly before applying.