Depression and Anxiety Trial, Not Yet Recruiting NCT06391723 Sponsor: Centre Hospitalier du Rouvray Condition: Depression and Anxiety
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Depression and Anxiety Trial, Not Yet Recruiting

NCT06391723
Not Yet Recruiting Not Applicable

voxsanity.com.au · Eligibility summary from public government registries · 18 August 2026 · not medical advice

Who may and may not be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who may be able to join

  • People who have been diagnosed with Major Depressive Disorder based on standard psychiatric diagnostic guidelines (DSM-5).
  • People who score 15 or higher on a standard depression rating scale called the Hamilton Depression Rating Scale (HAMD), indicating at least moderate depression.
  • For people with depression that is not related to bipolar disorder: their depression has not improved after trying at least two different antidepressant medications, each taken at the right dose for long enough during the current episode.
  • For people with bipolar disorder: their depression has not improved despite taking lithium at an appropriate level in the blood, combined with either lamotrigine or quetiapine at a full dose.
  • People whose antidepressant or mood-stabilising medication has not been changed for at least 15 days before joining.
  • People who have never previously received a treatment called repetitive Transcranial Magnetic Stimulation (rTMS), which uses magnetic pulses applied to the head.
  • People who have not taken benzodiazepines (a type of calming or anti-anxiety medication) or anti-epileptic medications for at least 15 days before joining.
  • People who can understand spoken and written French.
  • People who have given their informed, written consent to participate.

Who may not be able to join

Each point below is a reason the trial team may not be able to accept someone. It is not a list of requirements to meet.

  • People for whom Electroconvulsive Therapy (ECT), repetitive Transcranial Magnetic Stimulation (rTMS), MRI scans, or general anaesthesia are medically unsuitable or unsafe.
  • People who have received Electroconvulsive Therapy (ECT) within the last 6 months.
  • People who have poorly controlled epilepsy, or serious neurological or other major physical health conditions.
  • People who have a serious problem with substance use (other than tobacco or caffeine) based on standard psychiatric diagnostic guidelines (DSM-5).
  • People who have severe hearing difficulties.
  • People who have already been treated with any electrical or magnetic brain stimulation technique.
  • Women who do not have adequate contraception in place, or who are pregnant or breastfeeding.
  • People who are currently deprived of their freedom by an administrative or court order.
  • People who are currently participating in, or who have participated in, another interventional clinical trial within the 30 days before the enrolment visit for this trial.

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 8 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Phone: +33232956825

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Not Yet Recruiting
Phase
Not Applicable
Sponsor
Centre Hospitalier du Rouvray
Registry
ClinicalTrials.gov
Start date
1 June 2024
Est. completion
1 August 2026

This date has passed while the registry still lists the trial as open to participants. Sponsors often update a trial's status without revising its projected end date, so it may well still be recruiting — but the record is out of date in at least one respect. Check with the study contact before relying on either.

Primary endpoints

Response rate after 10 ECT

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 8 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov