Cardiomyopathy Trial, Recruiting NCT06431919 Sponsor: Post Graduate Institute of Medical Education and Research, Chandigarh Condition: Cardiomyopathy
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Cardiomyopathy Trial, Recruiting

NCT06431919
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People between 18 and 65 years of age
  • People who have been diagnosed with compensated cirrhosis (a form of liver scarring where the liver is still managing to function), confirmed through a liver biopsy, blood tests, or ultrasound scan
  • People whose heart scans (a type of echocardiogram) show a specific pattern of heart changes linked to liver disease, known as cirrhotic cardiomyopathy, with the heart still pumping well (ejection fraction above 50%)
  • People who have given written consent to take part in the trial

Who may not be able to join:

  • People over 65 years of age
  • People with significantly reduced kidney function, shown by a creatinine blood test result above 2 mg/dl
  • People who have taken a statin medication (a type of cholesterol-lowering drug) in the month before the study
  • People who have a medical reason they cannot take statins
  • People with more advanced liver disease, measured by a liver scoring system (CTP score above 9)
  • People with coronary artery disease (blocked or narrowed heart arteries)
  • People with certain heart rhythm or electrical problems, including sick sinus syndrome, a pacemaker, or heart valve disease
  • People with other heart conditions, including certain rhythm disorders or a type of heart muscle weakness that can occur around childbirth
  • People with specific complications involving the blood vessels between the lungs and liver (portopulmonary hypertension or hepatopulmonary syndrome)
  • People who have had a procedure to create a bypass channel in the liver (called a TIPS procedure)
  • People who have liver cancer (hepatocellular carcinoma)
  • People who are pregnant or breastfeeding
  • People living with HIV or who are on antiviral (retroviral) therapy
  • People with low haemoglobin levels — below 8 g/dl for women or below 9 g/dl for men — indicating anaemia
  • People who have had a serious bleeding episode from enlarged veins in the food pipe or stomach in the past 6 months
  • People who regularly take certain medications that are processed by a specific liver enzyme (CYP3A4), such as some blood pressure medicines, antifungal medicines, or HIV medicines (confirm with trial site)

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 23 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Dr Madhumita Premkumar, DM, Post Graduate Institute of Medical Education and Research, Chandigarh

Phone: 7087003409

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
Post Graduate Institute of Medical Education and Research, Chandigarh
Registry
ClinicalTrials.gov
Start date
10 June 2025
Est. completion
31 January 2028

Where this trial is recruiting

🇮🇳 India

Primary endpoints

Time to acute decompensation event

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 23 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov