Phase 2 Sleep Disorders Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- Adults between 18 and 65 years old
- People who have been diagnosed with moderate to moderately-severe sleep apnea, meaning their breathing stops or becomes shallow between 15 and 50 times per hour during a sleep study
Who may not be able to join:
- People who have been regularly using a CPAP or similar breathing machine (more than 4 hours a day, on at least 30% of nights, in the past 3 months)
- People who have been regularly using a tongue nerve stimulator device or a mouth appliance for sleep apnea (more than 4 hours a day, on at least 30% of nights, in the past 3 months)
- People who have had throat or airway surgery to treat sleep apnea (tonsil/adenoid removal is okay)
- People whose sleep study shows that more than 25% of their breathing pauses are caused by brain signalling issues rather than airway blockage
- People whose blood oxygen levels dropped very low (below 75%) for more than 5% of their sleep time during their sleep study
- People with a body mass index (a measure of body weight relative to height) above 45
- People who have had weight loss surgery but whose weight has not been stable (within 5%) for at least 6 months before joining
- People who are currently enrolled in a formal weight loss program
- People who have done shift work in the past 3 months
- People who work as commercial drivers or pilots
- People who have been in or nearly caused a car accident within the past year
- People who currently use recreational drugs, drink alcohol heavily as a habit, or test positive on a urine drug screen
- People with other sleep disorders, such as narcolepsy or restless legs syndrome
- People with an uncontrolled mood disorder or a diagnosis of schizophrenia
- People who have started a new antidepressant or antipsychotic medication within the past 3 months
- People whose medical records flag them as high-risk for suicide
- People with serious uncontrolled health conditions such as heart disease, irregular heartbeat, heart failure, serious lung disease, breathing failure, a stroke within the past 6 months, or chronic liver or kidney disease, or autoimmune disorders
- People who have taken sleep aid or sedative medications within the past 30 days
- People whose blood test results for blood cell count or liver function are significantly outside the normal range
- People who are pregnant
- People who are allergic to cannabinoids (cannabis-related substances) or sesame oil
- People who drink more than 10 alcoholic drinks per week on average
- People who have taken part in another clinical trial within the past 30 days
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Bharati Prasad, MD, Jesse Brown VA Medical Center, Chicago, IL
Phone: (312) 996-8433
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Apnea hypopnea index (AHI)
Can't join this trial?
Data last synced from ClinicalTrials.gov: 22 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.