Phase 3 Liver Cancer Trial, Recruiting

Written by an AI model from the ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• A laboratory test (tissue or cell sample) must have confirmed a cancer diagnosis.
• Participants must be 18 years or older and have an estimated life expectancy of more than 3 months.
• Liver function must fall within a specific range, measured by a scoring system called Child-Pugh class A or B (confirm with trial site for exact score requirements).
• General physical functioning must be reasonably good, as measured by a standard scale called the ECOG score (must be less than 2, meaning the person is able to carry out some daily activities).
• Blood clotting ability must be within an acceptable range, or any clotting problems must be reversible.
• Blood test results taken within 7 days before the procedure must meet specific levels for white blood cells, haemoglobin, platelets, clotting time, creatinine, albumin, and bilirubin (the trial site can confirm the exact numbers required).
• At least one measurable tumour must be present, as assessed using standard imaging criteria known as RECIST v1.1.
• Participants must be willing and able to attend scheduled visits, follow the treatment plan, and complete required laboratory tests.
• Appropriate birth control measures must be in place during the trial.
• Signed consent must be provided before joining.

Who may not be able to join:

• People who have taken part in another clinical trial of a drug or medical device within the past 4 weeks.
• People who have fluid build-up in the abdomen (ascites), a condition affecting brain function related to liver disease (hepatic encephalopathy), or bleeding from enlarged veins in the food pipe or stomach.
• People with serious other health conditions — such as significant heart disease, poorly controlled diabetes, or psychiatric disorders — that may affect outcomes.
• People who currently have, or have a past history of, another type of cancer.
• People who are pregnant or breastfeeding.
• People whose blood clotting tests fall outside the limits required for the procedure (platelet count below a certain level or clotting activity below 50%).
• People who require dialysis due to kidney failure or insufficiency.
• People with known severe hardening or narrowing of the arteries (confirm with trial site).
• People with uncontrolled high blood pressure above 160/100 mmHg.
• People with a known allergy to contrast dye used in imaging procedures.
• People taking medications that could interfere with how the study drugs are absorbed or processed by the body.
• People who, in the opinion of the investigating doctor, are not suitable for the trial for other reasons.
• People who are unlikely to follow the trial requirements reliably.

Important: Always verify eligibility with the trial site directly before applying.