Phase 2 Liver Cancer Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• A laboratory test (tissue or cell sample) has confirmed a cancer diagnosis.
• The person is willing and able to sign a consent form before joining the trial.
• The person is aged 18 or older and is expected to live for more than 3 months.
• Liver function falls within an acceptable range, measured by a scoring system called Child-Pugh class A or B (with a score above 7), and the person has a good general activity level (ECOG score below 2).
• Blood clotting ability is within an acceptable range, or any clotting problems can be reversed.
• Blood test results taken within 7 days before the procedure meet specific minimum levels for white blood cells, haemoglobin, platelets, clotting time, kidney function, albumin (a protein in the blood), and bilirubin (confirm with trial site for exact values).
• At least one tumour that can be measured using standard imaging guidelines (called RECIST v1.1).
• The person is using or agrees to use appropriate birth control during the trial.
• The person is willing and able to attend scheduled visits, follow the treatment plan, and complete required tests.

Who may not be able to join:

• People who have taken part in another clinical trial for a device or drug within the past 4 weeks.
• People who have fluid build-up in the abdomen (ascites), confusion caused by liver failure (hepatic encephalopathy), or bleeding from swollen veins in the stomach or oesophagus.
• People with serious other health conditions expected to affect their outcome, such as significant heart disease, poorly controlled diabetes, or psychiatric disorders.
• People who currently have, or have a past history of, another type of cancer.
• People who are pregnant or breastfeeding.
• People who are unlikely to follow the trial requirements reliably.
• People who have specific conditions making the procedure used in this trial unsafe, including: very low platelet counts or poor clotting ability; kidney failure requiring dialysis; severe hardening of the arteries; or blood pressure that cannot be controlled and is above 160/100 mmHg.
• People who are allergic to contrast dye used in imaging procedures.
• People taking medications that could affect how the study drugs are absorbed or processed by the body.
• People the trial investigators decide are not suitable for any other reason.

Important: Always verify eligibility with the trial site directly before applying.