Phase 1 Liver Cancer Trial, Recruiting NCT06487559 Sponsor: AbbVie Condition: Liver Cancer
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Phase 1 Liver Cancer Trial, Recruiting

NCT06487559
Recruiting Phase 1

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You have liver cancer (hepatocellular carcinoma, or HCC) that has spread to nearby tissues, other parts of the body, or cannot be removed with surgery
  • Your liver is still functioning reasonably well (a measure called Child-Pugh A — confirm with trial site)
  • Your liver cancer is classified as stage B or C according to a specific staging system called Barcelona Clinic Liver Cancer (confirm with trial site)
  • You are generally able to carry out daily activities with little or no limitation (scored 0 or 1 on a standard activity scale)
  • You have previously been treated with a type of cancer medication called an immune checkpoint inhibitor as your first treatment for HCC
  • Your blood counts and organ function (such as kidneys and liver) are at acceptable levels (confirm with trial site)

Who may not be able to join:

  • You have cancer that has spread to the brain or spinal cord and is causing symptoms, has not been treated, or is getting worse
  • You have had another type of cancer in the last 5 years, unless it was a cancer with a very low risk of spreading or being life-threatening
  • You have a history of conditions where your immune system attacks your own body, such as rheumatoid arthritis, lupus, multiple sclerosis, or inflammatory bowel disease, among others
  • You have had significant problems with your kidneys, nerves, mental health, hormones, heart, lungs, or liver in the last 6 months that could affect your ability to safely participate

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 28 July 2026
Phase 1: approximately ~10% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: ABBVIE INC., AbbVie

Phone: 844-663-3742

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 1
Sponsor
Registry
ClinicalTrials.gov
Start date
11 September 2024
Est. completion
1 October 2027

Where this trial is recruiting

🇨🇳 China

Primary endpoints

Percentage of Participants With Adverse Events (AE); Number of Participants with Dose-Limiting Toxicities (DLT); Maximum Plasma Concentration (Cmax) of Livmoniplimab and Budigalimab; Area Under the Serum Concentration Versus Time Curve (AUC) of Livmoniplimab and Budigalimab

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov