Phase 2 Liver Cancer Trial, Recruiting

Written by an AI model from the ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• You are 18 years of age or older at the time of signing the consent form.
• You have been diagnosed with liver cancer (hepatocellular carcinoma, or HCC), confirmed either by imaging scans using standard criteria or by a tissue biopsy.
• Your treatment plan includes a procedure to destroy the tumor (using radiofrequency or microwave ablation) or surgery to remove it, with the goal of curing the cancer.
• Your liver cancer is considered to have an intermediate, high, or very high chance of coming back after treatment.
• Your liver cancer is only in the liver, with no tumors larger than 1 cm found elsewhere in the body.
• You are generally able to carry out daily activities and care for yourself (as rated by a standard medical scale called ECOG performance status 0–1).
• If you have had or currently have hepatitis C, you must have finished hepatitis C treatment at least 1 month before the start of the trial.
• If you have hepatitis B, it must be well controlled, with a low virus level in your blood, and you may need to be on antiviral treatment — specific details should be confirmed with the trial site.
• Your kidneys, liver, and other organs are working well enough, as shown by blood tests taken within 14 days before the trial starts.

Who may not be able to join:

• You have a known allergy to shellfish, crabs, crustaceans, or any ingredient used in this trial.
• You currently have an active infection that requires treatment with medication.
• You have been diagnosed with an immune system deficiency, or you are currently taking high-dose steroid medication (more than 10 mg of prednisone per day or equivalent), or any other medication that suppresses your immune system within 7 days before the trial starts.
• You have an active autoimmune disease (where your immune system attacks your own body) that has needed medical treatment within the past 2 years — note that simple hormone replacement therapy such as thyroid medication or insulin does not count as this type of treatment.
• You have previously received an organ or tissue transplant from another person.
• You have a history of certain lung conditions, including idiopathic pulmonary fibrosis, organizing pneumonia, drug-caused lung inflammation, active tuberculosis, or unexplained lung inflammation (confirm with trial site).
• You have had certain liver treatments — such as alcohol ablation, chemoembolization, radiation to the liver, or similar procedures — within the last 3 months before the trial starts.
• You are currently taking or have recently taken (within approximately 3 weeks) certain medications, including cancer chemotherapy, other immune therapies, or high-dose steroids not related to managing a side effect.
• You have received a live vaccine within 28 days before the trial starts.

Important: Always verify eligibility with the trial site directly before applying.