Phase 3 Liver Cancer Trial, Recruiting NCT06555003 Sponsor: Tehran University of Medical Sciences Condition: Liver Cancer
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Phase 3 Liver Cancer Trial, Recruiting

NCT06555003
Recruiting Phase 3

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who have colorectal cancer that has spread to the liver, where the cancer cannot be fully removed by surgery or is on the borderline of being removable.
  • People who have not yet received chemotherapy for their metastatic (spread) disease.
  • People who are reasonably well and able to carry out daily activities (measured by a standard health scale called ECOG, with a score of 2 or less).
  • People whose blood, liver, and kidney are functioning well enough to meet specific laboratory test thresholds (confirm with trial site for exact values).

Who may not be able to join:

  • People whose cancer could be fully removed by surgery right away, without needing treatment beforehand.
  • People whose liver is 70% or more taken over by cancer.
  • People who have cancer that has spread to the brain or to the lining of the abdominal cavity (peritoneal carcinomatosis).
  • People who have cirrhosis (serious scarring of the liver).
  • People who have had an allergic reaction to any of the medications used in this trial.
  • People who have chronic hepatitis B or hepatitis C (long-term viral liver infections).

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 28 July 2026
Phase 3: approximately ~65% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Ali Jafarian, MD, Tehran University of Medical Sciences, Tehran, Iran

Phone: +989123193830

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 3
Sponsor
Tehran University of Medical Sciences
Registry
ClinicalTrials.gov
Start date
20 January 2025
Est. completion
1 October 2027

Where this trial is recruiting

Iran

Primary endpoints

Conversion to resectability: The proportion of patients who were initially deemed unresectable but, after undergoing specific intervention (Based on study arm) are reassessed for tumor shrinkage and found to be candidates for surgical resection.

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov