Phase 4 Sleep Disorders Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- Adults aged 18 to 80 years old
- People who have already been diagnosed with obstructive sleep apnea (OSA), or who score at moderate-to-high risk on a standard sleep apnea screening questionnaire called the STOP-Bang Questionnaire
- People who are already scheduled to have keyhole surgery (either chest or abdominal) under general anesthesia, where the operation is expected to last at least 1 hour, and where a pain relief pump controlled by the patient is planned for after surgery
Who may not be able to join:
- People diagnosed with central sleep apnea (a different type of sleep apnea that originates in the brain, rather than caused by a blocked airway)
- People with a history of schizophrenia, epilepsy, Parkinson's disease, or myasthenia gravis (a muscle weakness condition)
- People currently taking antipsychotic, antidepressant, or anti-anxiety medications
- People who are unable to communicate before surgery due to being in a coma, having severe dementia, or being deaf
- People with a history of drug or alcohol dependence, or who have used sedative or sleeping medications within the month before surgery
- People for whom the study drug ketamine would not be medically safe — for example, those with an overactive thyroid, a certain type of adrenal gland tumour (pheochromocytoma), or glaucoma
- People with certain heart rhythm problems, including sick sinus syndrome, a very slow heart rate (fewer than 50 beats per minute), or a significant heart conduction block, unless a pacemaker is already in place
- People for whom high-flow oxygen delivered through a nasal tube would not be medically safe — for example, those with air around the heart or in the chest cavity, very low blood pressure, fluid leaking from around the brain or spine, sinus or ear infections, or a significantly deviated nasal septum
- People with severely reduced liver function, severely reduced kidney function requiring dialysis or similar treatment, severely reduced heart function, or who are classified as having very serious overall health status (confirm with trial site for specific classifications)
- People expected to need to remain on a breathing tube in an intensive care unit after surgery
- People considered unsuitable for any other reason, as determined by the trial team
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Dong-Xin Wang, M.D., Peking University First Hospital
Phone: +86 152 1084 6532
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Subjective sleep quality during the first night after surgery.
Can't join this trial?
Data last synced from ClinicalTrials.gov: 7 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.