Sleep Disorders Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People who have been diagnosed with moderate or severe obstructive sleep apnea (a condition where breathing repeatedly stops during sleep)
• People who are currently using a CPAP machine with a nasal mask to treat their sleep apnea
• People whose CPAP data from the last 7 days shows a high level of unintended air leakage (above 24 litres per minute at the 95th percentile), or at least 4 sudden drops in leak over a single night
• People who still have ongoing excessive air leakage at the end of the first part of the study (called Study A)

Who may not be able to join:

• People who experience unintended air leaking from their mask or mask accessories (confirm with trial site, as this appears to overlap with inclusion criteria)
• People whose sleep study showed that central apnea — a type where the brain fails to signal the breathing muscles — was the main finding, rather than obstructive sleep apnea
• People with unstable heart disease, those who are confined to bed, or those living with a neurodegenerative disease, a severe psychiatric condition, or chronic obstructive pulmonary disease (COPD)
• People who have previously had surgery to treat obstructive sleep apnea
• People with severe nasal blockage, as measured by a score of 55 or higher on a standard nasal symptom questionnaire called the NOSE scale

Important: Always verify eligibility with the trial site directly before applying.