Fibromyalgia Trial, Recruiting NCT06574165 Sponsor: VA Office of Research and Development Condition: Fibromyalgia
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Fibromyalgia Trial, Recruiting

NCT06574165
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

For veterans living with fibromyalgia (FM):

  • People who are 19 years of age or older
  • People whose pain and symptom scores meet specific thresholds on standardised fibromyalgia assessment tools (confirm with trial site for exact score requirements)
  • People who have pain spread across at least 4 of 5 general body regions
  • People whose symptoms have been present at a similar level for at least 3 months
  • People who have a fibromyalgia diagnosis, even if other health conditions are also present
  • People whose PTSD symptoms — including at least one re-experiencing symptom, three avoidance symptoms, and two hyperarousal symptoms — have each been at a moderate level or higher in the past month, with a total severity score of 50 or higher

For veterans living without fibromyalgia:

  • People who are a similar age to participants in the fibromyalgia group

Who may not be able to join:

For veterans living with fibromyalgia:

  • People who have a neurological disorder
  • People with a body mass index (a measure of body weight relative to height) above 40
  • People who have chronic kidney disease
  • People with serious heart conditions, such as chronic heart failure, severe narrowing of heart valves, a history of cardiac arrest, an implanted defibrillator, or angina
  • People who have ischemic heart disease (reduced blood flow to the heart)
  • People who have used opioid pain medications daily for 90 days or more
  • People who take beta-blocker medications
  • People who are unable to give informed consent to participate in the study
  • People with a known diagnosis of dementia or significant cognitive impairment
  • People for whom MRI scanning is not safe (confirm with trial site for specific contraindications)
  • People who are pregnant

For veterans living without fibromyalgia:

  • People who are currently taking medications that affect how the body responds to pain
  • People who have a neurological disorder
  • People with a body mass index above 40
  • People for whom MRI scanning is not safe (confirm with trial site for specific contraindications)
  • People who are pregnant

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 19 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Taylor L Taylor, Birmingham VA Medical Center, Birmingham, AL

Phone: (205) 996-7937

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Registry
ClinicalTrials.gov
Start date
1 November 2024
Est. completion
1 October 2026

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Dispositional Trait Styles; Feasibility; Clinical Pain Severity; Pain Threshold; Temporal Summation of Pain; Conditioned Pain Modulation; C-reactive protein; Tumor necrosis factor- alpha; Interleukin-6; Interleukin- 10; Interleukin- 8; Myo-inositol; N-acetylaspartate; Choline; Lactate; Creatine; Brain Temperature; Exercise Benefits and Barriers; Exercise Perceptions

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 19 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov