Heart Disease Trial, Recruiting NCT06580392 Sponsor: Impulse Dynamics Condition: Heart Disease
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Heart Disease Trial, Recruiting

NCT06580392
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • Adults aged 18 or older who have been diagnosed with heart failure that causes symptoms.
  • People whose heart is pumping at 40% or less of its normal capacity (a condition called heart failure with reduced ejection fraction), confirmed by a heart scan taken within the last 6 months or earlier if results are available.
  • People who already have a cardiac resynchronisation therapy (CRT) device implanted, provided it was put in more than 1 year ago and their heart failure symptoms are classified as severe (NYHA Class III or IV) (confirm with trial site).

Who may not be able to join:

  • People who are considered unlikely to follow their prescribed medical treatment, for reasons other than side effects or medical reasons why a treatment cannot be used.
  • People with a QMS score above 5 — this is a specific measurement used by the trial team (confirm with trial site for details).
  • People whose kidneys are functioning below a certain level (an eGFR reading below 15).
  • People who already have a CRT device implanted and whose heart has responded well to that device.
  • People for whom a CRT device is already strongly recommended as a first-line treatment under medical guidelines.
  • People with other serious health conditions that may affect the trial's assessments or results.
  • People who have medical reasons preventing them from receiving the study's treatment (CCM therapy) or from having a device implanted.
  • People with severe narrowing of one or more heart valves.

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 14 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Phone: (856) 642-9933

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
Impulse Dynamics
Registry
ClinicalTrials.gov
Start date
1 February 2025
Est. completion
1 June 2027

Where this trial is recruiting

🇮🇹 Italy

Primary endpoints

Change in Quad Medication Score

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 14 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov