Phase 2 Liver Cancer Trial, Recruiting NCT06590259 Sponsor: Shanghai 6th People's Hospital Condition: Liver Cancer
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Phase 2 Liver Cancer Trial, Recruiting

NCT06590259
Recruiting Phase 2

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People between 18 and 75 years of age (any gender)
  • People who have been diagnosed with colorectal cancer that has spread to the liver, where the liver tumours cannot be surgically removed, or where surgery is not tolerated or has been declined
  • People whose original bowel cancer cannot be removed or has come back, but without serious complications such as active bleeding or blockage
  • People whose first treatment has stopped working, with the cancer having progressed or new liver tumours having appeared
  • People with no more than 5 liver tumours, where the largest single tumour measures 3 cm or smaller
  • People who have had previous chemotherapy, radiation, or local liver treatments, provided at least 1 month has passed since the last treatment
  • People with liver function rated as Child-Pugh A or B, and blood test results within acceptable ranges for bilirubin, creatinine, white blood cell count, and platelets (confirm specific values with trial site)
  • People with a general health/activity level rated as ECOG 0, 1, or 2 — meaning able to carry out at least limited self-care (confirm with trial site)
  • People who are willing to receive follow-up treatment that includes an anti-PD-1 immunotherapy medicine

Who may not be able to join:

  • People with severely reduced liver function, rated as Child-Pugh class C
  • People whose expected survival is less than 3 months
  • People with serious failure of a major organ (such as the heart, lungs, or kidneys)
  • People with a currently active infection
  • People with permanent, irreversible problems with blood clotting
  • People with large amounts of fluid build-up in the abdomen or chest that has not responded to treatment, or with severe unintentional weight loss and muscle wasting
  • People who are unable to cooperate with the treatment process
  • People the trial investigators consider unsuitable for any other reason that may affect safe participation in the study

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 26 July 2026
Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Chief physician of Medical Oncology, Shanghai 6th People's Hospital

Phone: 13816067266

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 2
Sponsor
Shanghai 6th People's Hospital
Registry
ClinicalTrials.gov
Start date
12 March 2024
Est. completion
1 July 2027

Where this trial is recruiting

🇨🇳 China

Primary endpoints

Progression Free Survival (PFS)

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 26 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov