Liver Cancer Trial, Recruiting NCT06622031 Sponsor: Sun Yat-sen University Condition: Liver Cancer
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Liver Cancer Trial, Recruiting

NCT06622031
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who have been diagnosed with primary liver cancer (hepatocellular carcinoma), confirmed by a biopsy or by standard clinical diagnostic guidelines
  • People who have a blood clot or tumour invasion in the main vein supplying the liver (called portal vein tumour thrombus), rated as Grade III or IV using a specific medical grading system called Cheng's criteria
  • People whose portal vein blockage has caused increased pressure in the surrounding blood vessels (portal hypertension)
  • People who may or may not have experienced bleeding from swollen veins caused by this portal vein blockage
  • People whose cancer has spread to no more than five spots in total, across no more than two organs outside the liver
  • People with no more than five tumours within the liver itself
  • People who are receiving Lenvatinib and a PD-1 inhibitor as their first course of systemic (whole-body) treatment
  • People whose liver function is rated as Child-Pugh class A or B, and whose general physical ability is rated 0 or 2 on a standard medical scale (ECOG scale)
  • People with no history of any other type of cancer
  • People who have agreed to take part in this clinical trial
  • People whose blood test results meet specific thresholds for white blood cells, red blood cells, platelets, liver enzymes, and kidney function (confirm with trial site for exact values)

Who may not be able to join:

  • People whose liver cancer has come back after previous treatment (recurrent HCC)
  • People whose portal vein tumour thrombus is rated as Grade I or II by Cheng's criteria
  • People younger than 18 years old or older than 75 years old
  • People whose cancer has spread to more than five sites outside the liver
  • People with more than five tumours within the liver
  • People whose cancer has not responded to Lenvatinib
  • People whose life expectancy is estimated to be less than 3 months

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 7 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Feng Duan, Chinese PLA General Hospital

Phone: 86 19868000115

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Registry
ClinicalTrials.gov
Start date
1 October 2024
Est. completion
1 December 2026

Where this trial is recruiting

🇨🇳 China

Primary endpoints

Rates of gastrointestinal hemorrhage

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 7 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov