Phase 2 HIV and AIDS Trial, Recruiting NCT06624839 Sponsor: University of Maryland, Baltimore Condition: HIV and AIDS
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Phase 2 HIV and AIDS Trial, Recruiting

NCT06624839
Recruiting Phase 2

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who are aged 18 to 70 years old
  • People who are able to give their informed consent to participate
  • People who have not previously received the Gardasil 9 HPV vaccine, or who are unsure of their vaccination history and were born before 2003 (having received a different HPV vaccine, such as the bivalent or quadrivalent type, is still allowed)
  • People who were born male

For the Test Group (HIV-positive participants):

  • People living with HIV
  • People who currently use, or have previously used, androgen blockers or estradiol (a form of estrogen)

For the Control Group (HIV-negative participants):

  • People who do not have HIV
  • Either: people who currently use, or have previously used, androgen blockers or estradiol; OR people who have never used these medications AND have had sex with a person with a penis in the past year

Who may not be able to join:

  • People younger than 18 or older than 70 years old
  • People who have already received the nine-valent HPV vaccine (Gardasil 9), or who are unsure of their vaccination history and were born after 2003
  • People who were born female
  • People who have had a severe allergic reaction to yeast or any other ingredient in the vaccine
  • People who have received certain medical treatments in the past 6 months, including chemotherapy, specific immune-system-affecting medications (such as rituximab or ibrutinib), intravenous or subcutaneous immunoglobulin, radiation therapy, or other immune-modifying treatments (confirm with trial site)

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 28 July 2026
Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Omar Harfouch, MD, University of Maryland, Baltimore

Phone: 410-706-1372

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 2
Registry
ClinicalTrials.gov
Start date
15 March 2025
Est. completion
1 January 2027

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Immunogenicity of the human papillomavirus (HPV) vaccine in BM-EABE (people born male with current or past exposure to androgen blockers or estrogen (BM-EABE) with and without HIV

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov