Phase 3 Heart Disease Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- People who are 18 years of age or older
- People who are experiencing a sudden worsening of chronic heart failure (CHF)
- People who have signs of liver problems, shown through blood tests or a liver ultrasound
- People who have a history of chronic heart failure and have previously taken a type of water pill (loop diuretic) by mouth
- People who are expected to need diuretic treatment given through a drip (IV) for at least 72 hours
- There is no requirement related to how well the heart is pumping (ejection fraction)
Who may not be able to join:
- People experiencing cardiovascular collapse, which includes very low blood pressure (below 90 mmHg), a sudden large drop in blood pressure lasting 15 minutes or more with signs of poor blood flow to organs, a need for certain heart-strengthening medications (not including digoxin), or a need for CPR
- People whose liver problems are caused by something other than heart failure
- People with severe anaemia (very low red blood cell levels, specifically haemoglobin below 8 g/dL)
- People with very high blood pressure that is not under control, or a blood pressure emergency
- People with severe fluid build-up in the lungs that requires medication through a drip (IV vasodilators) to manage
- People with significantly reduced kidney function, shown by certain blood test results (creatinine above 3 mg/dL or a kidney filtration rate below 30 ml/min)
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: MARIOS VASILEIOS KOUTROULOS, University Hospital of Alexandroupolis
Phone: +30 6942862493
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Assessment of symptoms; Change in the serum creatinine level
Can't join this trial?
Data last synced from ClinicalTrials.gov: 6 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.