Cardiomyopathy Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• You are 12 years old or older at the time of signing the consent form
• You are able and willing to sign a consent form and follow the study's rules and requirements
• You have been diagnosed with a heart condition called arrhythmogenic cardiomyopathy (ACM), a disease affecting the heart muscle and its rhythm
• Genetic testing done by an approved laboratory has found a specific harmful change (variant) in a gene called PKP2 linked to your condition
• You had a defibrillator (ICD) implanted at least 6 months before joining the study
• A heart scan (echocardiogram or MRI) done within the past 12 months shows your heart's pumping function (left ventricular ejection fraction) is at 50% or above

Who may not be able to join:

• Your genetic test results suggest your heart condition may be caused by a gene change other than a specific type of PKP2 variant
• You are currently taking part in another clinical trial using an experimental treatment that could affect this study's results
• You have previously taken part in a study involving gene therapy or gene editing
• You have very severe heart failure (known as NYHA Class IV), meaning you have symptoms even at rest
• You currently need, or are expected to need within 6 months, a mechanical device to help your heart pump, or a heart transplant
• You have previously had a heart transplant or transplant of another major organ (such as lungs or liver)
• Your heart has been found within the past 12 months to rely entirely on a pacemaker to beat
• You have tested positive for HIV
• You are unwilling or unable to follow the study's procedures, attend follow-up appointments, or cooperate fully with the research team

Important: Always verify eligibility with the trial site directly before applying.