Heart Disease Trial, Recruiting NCT06678594 Sponsor: Royal College of Surgeons, Ireland Condition: Heart Disease
Back to Heart Disease

Heart Disease Trial, Recruiting

NCT06678594
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who have documented evidence of reduced blood flow to the heart muscle (confirm with trial site)
  • People who have at least one coronary artery with moderate to severe calcium buildup, confirmed by imaging, with a significant narrowing of the artery that is suitable for a procedure to open the artery
  • People whose blocked artery can be crossed with a thin guidewire used during heart procedures
  • People aged 18 years or older
  • People who are willing and able to follow the study procedures and attend follow-up appointments

Who may not be able to join:

  • People who are in cardiogenic shock (when the heart suddenly cannot pump enough blood to meet the body's needs)
  • People who are having a certain type of serious heart attack called an ST-segment elevation myocardial infarction
  • People who have a narrowing inside a previously placed stent
  • People who have had a blood clot form inside a stent
  • People who have a tear in a coronary artery wall
  • People who have a completely blocked major coronary artery
  • People whose heart pumping function is significantly reduced (below 30%)
  • People who need open-heart bypass surgery
  • People with a documented allergy to everolimus or to any stent material
  • People who cannot take two blood-thinning medications together for at least 3 months (unless they are already on a blood-thinning tablet taken by mouth)
  • People who are pregnant, breastfeeding, or planning to become pregnant within one year
  • People with a life expectancy of less than one year
  • People who are already taking part in another clinical trial involving an investigational treatment
  • People who are unable to give informed consent

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 22 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Robert A Byrne, RCSI University of Medicine and Health Sciences

Phone: 00353858802094

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
Royal College of Surgeons, Ireland
Registry
ClinicalTrials.gov
Start date
24 September 2024
Est. completion
23 March 2026

Where this trial is recruiting

🇮🇪 Ireland

Primary endpoints

Minimum stent area (MSA); Target lesion failure (TLF)

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 22 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov